GW22756

Anti-Endoglin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• MDL number: MFCD01094408
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: chicken
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 제조업체/상표: Genway 15-288-22756
• 기술: western blot: suitable
• NCBI 수납 번호: NP_000109.1
• UniProt 수납 번호: P17813
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ENG(2022)

설명

면역원

Immunogen Sequence: GI # 4557555, sequence 341-470

Recombinant endoglin

애플리케이션

Anti-Endoglin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

생화학적/생리학적 작용

Endoglin is a type I transmembrane glycoprotein located on cell surfaces belonging to the transforming growth factor β superfamily. It is commonly referred to as CD105, END, HHT1 and ORW1. It is a part of the TGF β receptor complex, which plays an important role in angiogenesis. CD105 expression correlates with prognosis for several cancers and plays an important role in the pancreatic cancer microenvironment. Tumoral CD105 acts as an independent predictive marker for death risk.[1] Mutation in endoglin causes a vascular defect, hereditary hemorrhagic telangiectasia (HHT1).

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)