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Merck
모든 사진(1)

문서

F4641

Sigma-Aldrich

Anti-Human IgG3−FITC antibody, Mouse monoclonal

clone HP-6050, purified from hybridoma cell culture

동의어(들):

Monoclonal Anti-Human IgG3

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

mouse

결합

FITC conjugate

항체 형태

purified immunoglobulin

항체 생산 유형

secondary antibodies

클론

HP-6050, monoclonal

형태

buffered aqueous solution

저장 조건

protect from light

기술

dot immunobinding: 1:64
particle immunofluorescence: 1:8

동형

IgG1

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Human Immunoglobulin G consists of four subclasses, namely IgG1, IgG2, IgG3, and IgG4, named γ1, γ2, γ3, and γ4, respectively. The primary structure of the antibody contains disulfide bonds involved in linking the two heavy chains,and linking the heavy and light chains. IgG3, a pro-inflammatory antibody, appears first in the course of a viral infection and induces effector functions.

특이성

The antibody is specific for human IgG3 and is non-reactive with other IgG subclasses. This clone has been recommended by the IUIS/WHO study for its specificity and reactivity in a wide range of assay protocols and techniques.

애플리케이션

Monoclonal Anti-Human IgG3-FITC antibody produced in mouse has been used in immunohistochemistry and indirect immunofluorescence.

물리적 형태

Solution in 0.01 M phosphate buffer, pH 8.0, containing 1% inactivated bovine serum albumin and 15 mM sodium azide.

저장 및 안정성

For continuous use, store at 2-8 °C for up to one month.
For extended storage, solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.

기타 정보

In order to obtain best results, it is recommended that each individual user determine working dilutions by titration assay.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Erdem Tüzün et al.
Acta neuropathologica, 118(6), 737-743 (2009-08-15)
We report the immunopathological analysis of the brain and tumor of two patients who died of anti-NMDAR-associated encephalitis, and of the tumor of nine patients who recovered. Findings included prominent microgliosis and deposits of IgG with rare inflammatory infiltrates in
Seroprevalence of human herpesvirus 6 in Andino Pune?os (Argentina)
Romagnoli, Pablo Alberto, et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 669-672 (2000)
Antibody structure, instability, and formulation.
Wang W, et al.
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)
IgG Subclasses and Allotypes: From Structure to Effector Functions
Gestur V, et al.
Frontiers in Immunology (2014)
Tiffany N Caza et al.
Kidney360, 1(6), 491-500 (2020-04-21)
Common variable immunodeficiency (CVID) is one of the most common primary immunodeficiency syndromes, affecting one in 25,000-50,000 people. Renal insufficiency occurs in approximately 2% of patients with CVID. To date, there are no case series of renal biopsies from patients

문서

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