Extracellular domain of human ephrin-A4 (amino acids 1-203) was fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.
생화학적/생리학적 작용
Member of the ephrin ligand family that binds Eph receptor tyrosine kinases (EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and Eph8). Involved in pattern formation and morphogenesis.
Member of the ephrin ligand family that binds Eph receptor tyrosine kinases (EphA2, through Eph8); involved in pattern formation and morphogenesis.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
분석 메모
The biological activity is measured by its ability to compete with biotinylated human Ephrin-A5/Fc chimera for binding with recombinant mouse EphA3/Fc in ELISA.
We previously reported that EphA4, a member of the Eph family of receptor tyrosine kinases, is an important modulator of growth hormone (GH) signaling, leading to augmented synthesis of insulin-like growth factor 1 (IGF1) for postnatal body growth. In the
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