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Merck
모든 사진(1)

주요 문서

D8907

Sigma-Aldrich

1,2-Dioctanoylethylene glycol

~99%

동의어(들):

Ethylene glycol dioctanoate

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About This Item

실험식(Hill 표기법):
C18H34O4
CAS Number:
Molecular Weight:
314.46
MDL number:
UNSPSC 코드:
41106300
PubChem Substance ID:

분석

~99%

양식

liquid

저장 온도

−20°C

SMILES string

CCCCCCCC(=O)OCCOC(=O)CCCCCCC

InChI

1S/C18H34O4/c1-3-5-7-9-11-13-17(19)21-15-16-22-18(20)14-12-10-8-6-4-2/h3-16H2,1-2H3

InChI key

HTNFLUQQANUSLR-UHFFFAOYSA-N

생화학적/생리학적 작용

Potent inhibitor of sn-1,2-diacylglycerol phosphorylation in vitro.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

S Bourgoin et al.
The Journal of biological chemistry, 267(17), 11908-11916 (1992-06-15)
To determine the role of protein tyrosine phosphorylation in the activation of phospholipase D (PLD), electropermeabilized HL-60 cells labeled in [3H]alkyl-phosphatidylcholine were treated with vanadate derivatives. Micromolar concentrations of vanadyl hydroperoxide (V(4+)-OOH) induced accumulation of tyrosine-phosphorylated proteins. Concomitantly, V(4+)-OOH or
S E Severin et al.
FEBS letters, 232(2), 286-288 (1988-05-23)
Diol lipids (dioleoyl- and dioctanoylethylene glycol) at relatively low concentrations (approximately 10 microM) were found to activate significantly protein kinase C in the presence of phosphatidylserine or phosphatidylinositol. Since diol lipids are widespread minor lipid constituents of many cells [(1974)
M Tóth
Biochimica et biophysica acta, 1210(1), 105-112 (1993-12-02)
Metabolic conversion of the synthetic DAG, dioctanoylglycerol (DOCG) into the dioctanoyl species of phosphatidic acid (PADOCG) and phosphatidylcholine (PCDOCG) in minced human primordial placenta incubated with [32P]phosphate was studied. Time-course experiments performed with 0.25 mM DOCG revealed a much higher
W R Bishop et al.
The Journal of biological chemistry, 261(15), 6993-7000 (1986-05-25)
Diacylglycerol kinase is though to play a central role in the metabolism of diacylglycerol second messengers in agonist-stimulated cells. A series of diacylglycerol analogs were tested for their ability to act as substrates or inhibitors of diacylglycerol kinase with the
P Nasmith et al.
Biochemical and biophysical research communications, 161(1), 95-100 (1989-05-30)
The diacylglycerol kinase inhibitors, R59022 and dioctanoylethylene glycol (diC8-eg), potentiate stimulation of the respiratory burst by the chemotactic tripeptide N-formyl-methionyl-leucyl-phenylalanine (fMLP) in human neutrophils. However, in contrast to the potentiation observed in intact cells, neither R59022 nor diC8-eg enhanced the

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