D8668

2′-Deoxyadenosine monohydrate

powder, BioReagent, suitable for cell culture

• 동의어(들): 9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside
• 실험식(Hill 표기법): C₁₀H₁₃N₅O₃ · H₂O
• CAS Number: 16373-93-6
• Molecular Weight: 269.26
• Beilstein: 91015
• EC Number: 213-488-7
• MDL number: MFCD00005754
• UNSPSC 코드: 12352207
• PubChem Substance ID: 24894112
• NACRES: NA.75

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥99% (HPLC)
• 형태: powder
• 기술: cell culture | mammalian: suitable
• solubility: H₂O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
• 저장 온도: 2-8°C
• SMILES string: [H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
• InChI: 1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
• InChI key: OLXZPDWKRNYJJZ-RRKCRQDMSA-N

설명

애플리케이션

2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:

• To study the importance of homologous recombination at the interface between replication and mitosis
• To analyze deoxynucleoside-assisted transductions
• To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells

2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.

생화학적/생리학적 작용

Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves