D7444

p38δ, active, GST tagged human

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 동의어(들): MAPK13, PRKM13, SAPKA4
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 재조합: expressed in baculovirus infected Sf9 cells
• Quality Level: 200
• 제품 라인: PRECISIO^® Kinase
• 분석: ≥70% (SDS-PAGE)
• 양식: buffered aqueous glycerol solution
• 특이 활성도: 220-298 nmol/min·mg
• 분자량: ~71 kDa
• UniProt 수납 번호: O15264
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... MAPK13(5603)

설명

생화학적/생리학적 작용

p38d (SAPK4) is a member of the p38 MAPK family and is activated by chemical and environmental stresses as well as by proinflammatory cytokines. p38d has a TGY dual phosphorylation motif and is activated in response to cellular stresses and proinflammatory cytokines.MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.

물리적 형태

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

법적 정보

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)