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Merck
모든 사진(1)

주요 문서

D0670

Sigma-Aldrich

Dihydroouabain

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About This Item

실험식(Hill 표기법):
C29H46O12
CAS Number:
Molecular Weight:
586.67
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:

SMILES string

[H][C@@]12CC[C@]3(O)C[C@H](C[C@@H](O)[C@]3(CO)[C@@]1([H])[C@H](O)C[C@]4(C)[C@H](CC[C@]24O)[C@H]5COC(=O)C5)O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O

InChI

1S/C29H46O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h13-19,21-25,30-32,34-38H,3-12H2,1-2H3/t13-,14?,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1

InChI key

ZTFGOPUOTATSAL-CFVDWFIMSA-N

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생화학적/생리학적 작용

Cardiac glycoside; an inhibitor of the sodium-potassium pump.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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문서 라이브러리 방문

Isamu Ito et al.
Investigative ophthalmology & visual science, 47(2), 683-692 (2006-01-25)
To evaluate the effect of acute exposure to high glucose on myogenic tone and reactivity of the rat ophthalmic artery and to compare the observations with that in ophthalmic artery from a diabetic rat model. Ophthalmic arteries from Sprague-Dawley rats
N A Delamere et al.
Investigative ophthalmology & visual science, 39(5), 763-768 (1998-04-16)
In a previous study, an increase in Na,K-ATPase alpha 2 expression was detected in the epithelium of porcine lenses exposed to amphotericin B, an ionophore that also increases lens sodium and stimulates active sodium transport. The purpose of the present
Raimondo D'Ambrosio et al.
Journal of neurophysiology, 87(1), 87-102 (2002-01-11)
Little information is available on the specific roles of different cellular mechanisms involved in extracellular K(+) homeostasis during neuronal activity in situ. These studies have been hampered by the lack of an adequate experimental paradigm able to separate K(+)-buffering activity
Akiyuki Taruno et al.
Neuroscience research, 72(2), 117-128 (2011-11-22)
A glutamatergic end-bulb synapse in the avian nucleus magnocellularis relays temporal sound information from the auditory nerve. Here, we show that presynaptic Na(+)/K(+)-ATPase (NKA) activity at this synapse contributes to the maintenance of the readily releasable pool (RRP) of vesicles
K Quinn et al.
American journal of physiology. Heart and circulatory physiology, 279(1), H351-H360 (2000-07-19)
Electrogenicity of the Na(+)/K(+) pump has the capability to generate a large negative membrane potential independently of ion-channel current. The high background membrane resistance of arterioles may make them susceptible to such an effect. Pump current was detected by patch-clamp

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