C7688

Chaperonin 60 from Escherichia coli

>95% (SDS-PAGE), recombinant, expressed in E. coli overproducing strain, lyophilized powder

• 동의어(들): Cpn60, GroEL
• MDL number: MFCD00163256
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: Escherichia coli
• Quality Level: 200
• 재조합: expressed in E. coli overproducing strain
• 분석: >95% (SDS-PAGE)
• 형태: lyophilized powder
• 기술: electron microscopy: suitable; mass spectrometry (MS): suitable
• 적합성: passes test (Refolding (w/GroES))
• UniProt 수납 번호: P10809
• 저장 온도: 2-8°C
• 유전자 정보: human ... HSPD1(3329)

설명

일반 설명

Research area: Cell Signaling

Chaperonin 60 (GroEL) and chaperonin 10 (GroES) belong to the ubiquitous family of heat-shock molecular chaperones found in prokaryotes and in eukaryotic organelles.

애플리케이션

Chaperonin 60 from Escherichia coli has been used:

• in mass spectroscopy
• in cryo-electron microscopy imaging as control for testing particle distribution
• as standard in infrared spectrum measurements
• as a protein sample for stability assessment and characterization studies using differential mobility analysis (DMA) and cryo-electron microscopy (cryo-EM).

생화학적/생리학적 작용

Apart from its role in facilitating protein folding, chaperonin 60 (Cpn60) serves as an extracellular signaling protein, showing functional similarities to certain proinflammatory cytokines. Furthermore, Cpn60 contributes to the inhibition of lipid accumulation and adipogenesis during the initial stages of cellular differentiation, thereby exerting anti-obesity effects.

포장

Package size based on protein content.

물리적 형태

Lyophilized powder containing Tris buffer salts, potassium chloride, magnesium chloride, dithiothreitol, and trehalose as stabilizer.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)