C7673

Monoclonal Anti-CD14 antibody produced in mouse

clone UCHM-1, purified immunoglobulin, buffered aqueous solution

• 동의어(들): Monoclonal Anti-CD14
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: UCHM-1, monoclonal
• 양식: buffered aqueous solution
• 분자량: antigen 55 kDa
• 종 반응성: human
• 기술: flow cytometry: 5 μL using 1 × 10⁶ cells
• 동형: IgG2a
• UniProt 수납 번호: P08571
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CD14(929)

설명

특이성

The epitope recognized by this clone is sensitive to routine formalin fixation and paraffin embedding. Cryostat sections, post-fixed in formalin can be stained.
3rd Workshop: code no. 203
4th Workshop: code no. M24

면역원

human thymocytes followed by peripheral blood T cells.

애플리케이션

Monoclonal Anti-CD14 antibody produced in mouse is suitable for the following applications:

• Flow cytometry at a dilution of 5μL using 1 × 106 cells
• Immunofluorescence.
• Immunoblotting.

생화학적/생리학적 작용

CD14 gene has an important role during signaling of the innate immune response and in the detection of inflammatory pathogens. It also plays an important role in recognizing tuberculosis (TB) disease and it can be used as a potential biomarker for predicting the prognosis of breast invasive ductal carcinoma with LN+ER/PR-Her²⁺. It is also associated with asthma, croup and allergy.

표적 설명

CD14 is a phosphoinositol-linked, single-chain, human cell surface glycoprotein antigen which is found on most human peripheral blood monocytes, granulocytes and dendritic reticulum cells, and some tissue macrophages. CD14 may also be present on B cells. Soluble forms of CD14 are present in serum and urine. The antigen functions as an acceptor for LPS-binding protein complexes.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable