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Merck
모든 사진(1)

주요 문서

C7518

Sigma-Aldrich

L-Carnitine hydrochloride

≥97%, from equine muscle

동의어(들):

(−)-β-Hydroxy-γ-(trimethylammonio)butyrate, Vitamin BT

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About This Item

Linear Formula:
(CH3)3N+CH2CH(OH)CH2CO2H · Cl-
CAS Number:
Molecular Weight:
197.66
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:

생물학적 소스

equine muscle

분석

≥97%

저장 온도

−20°C

SMILES string

[Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O

InChI

1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/t6-;/m1./s1

InChI key

JXXCENBLGFBQJM-FYZOBXCZSA-N

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생화학적/생리학적 작용

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.

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제품 번호
설명
가격

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Johana Vásquez-Procopio et al.
Metallomics : integrated biometal science, 12(2), 218-240 (2019-12-05)
Manganese is considered essential for animal growth. Manganese ions serve as cofactors to three mitochondrial enzymes: superoxide dismutase (Sod2), arginase and glutamine synthase, and to glycosyltransferases residing in the Golgi. In Drosophila melanogaster, manganese has also been implicated in the
Aris A Polyzos et al.
Cell metabolism, 29(6), 1258-1273 (2019-04-02)
The basis for region-specific neuronal toxicity in Huntington disease is unknown. Here, we show that region-specific neuronal vulnerability is a substrate-driven response in astrocytes. Glucose is low in HdhQ(150/150) animals, and astrocytes in each brain region adapt by metabolically reprogramming
Silvana Constantinescu et al.
Canadian journal of physiology and pharmacology, 93(11), 913-922 (2015-09-26)
We have shown that reduced expression of receptor-interacting protein 140 (RIP140) alters the regulation of fatty-acid (FA) oxidation in muscle. To determine whether a high level of FA availability alters the effects of RIP140 on metabolic regulation, L6 myotubes were
Vladimir V Dynnik et al.
PloS one, 10(7), e0134145-e0134145 (2015-07-29)
The aim of present study was to investigate the effects of ammonium ions on in vitro neuronal network activity and to search alternative methods of acute ammonia neurotoxicity prevention. Rat hippocampal neuronal and astrocytes co-cultures in vitro, fluorescent microscopy and

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