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Merck
모든 사진(1)

주요 문서

C7397

Sigma-Aldrich

Cyclophosphamide monohydrate

ISOPAC®

동의어(들):

2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan

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크기 선택

1 G
₩295,974

₩295,974


출고 가능일2025년 4월 09일세부사항


벌크 견적 요청

크기 선택

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1 G
₩295,974

About This Item

실험식(Hill 표기법):
C7H15Cl2N2O2P · H2O
CAS Number:
Molecular Weight:
279.10
Beilstein:
4678992
EC Number:
MDL number:
UNSPSC 코드:
51112507
PubChem Substance ID:
NACRES:
NA.25

₩295,974


출고 가능일2025년 4월 09일세부사항


벌크 견적 요청

분석

97.0-103.0% (HPLC)

양식

powder

mp

49-51 °C (lit.)

저장 온도

2-8°C

SMILES string

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI key

PWOQRKCAHTVFLB-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Cyclophosphamide, a nitrogen mustard DNA alkylating agent, is used to study its mechanisms of action as an anticancer and antiimmunity drug.

생화학적/생리학적 작용

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations.

포장

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

주의사항

Injecting a compatible solvent directly into the vial permits preparation of any desired strength solution without exposure.

재구성

Dissolving the contents in 100 mL of solvent yields a 1% solution.

법적 정보

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

ISOPAC

제품 번호
설명
가격

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

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Lupus nephritis remains one of the most severe manifestations of systemic lupus erythematosus associated with considerable morbidity and mortality. A better understanding of the pathogenesis of lupus nephritis is an important step in identifying more targeted and less toxic therapeutic
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문서

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

질문

1–4 / 4 질문  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 답변
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 답변
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. How should stock solutions for item C7397-1G, Cyclophosphamide monohydrate be stored?

    1 답변
    1. The stock solution should be stored at 0 - 4°C for short-term use or at -20°C for long-term storage.

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  4. what is the difference between C7397 & C0768?

    1 답변
    1. Both Product C7397 and C0768 fall under the same Chemical Abstract Service number (CAS) 6055-19-2, which means chemically they are the same. Both products are also offered in a powdered format. These products are suitable for the application of cyclophosphamide.

      The differences between the two materials is that product C7397 is only offered in 1 gram pack size. It is also apart of the ISOPAC portfolio, which are products that are packaged in special packaging for sensitive and hazardous chemical. This product is specifically packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal. This specialized packaging allows for injection of a compatible solvent directly into the vial to any desired strength solution without exposure of the material to the air. Product C0768 is offered in 1 gram, 5 grams, 10 grams, and 25 grams. All pack sizes are packaged in a glass bottle and bulk packaging is an available option for this material.

      Product C7397 has a quality level of 100 while product C0768 has a quality level of 200. Products with quality level 100 are designed for non-regulated applications with no change notification requirements. Products with quality level of 200 are designed for non-regulated applications with limited change notification requirements.

      The specifications for each product are slightly different as well, please view the specification sheets for both items:
      https://www.sigmaaldrich.com/specification-sheets/473/595/C7397-BULK________SIGMA____.pdf
      https://www.sigmaaldrich.com/specification-sheets/989/258/C0768-BULK________SIGMA____.pdf

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