C6895
Cefaclor
동의어(들):
7-(D-2-Amino-2-phenylacetamido)-3-chloro-3-cephem-4-carboxylic acid
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100 MG
₩47,198
1 G
₩438,886
About This Item
실험식(Hill 표기법):
C15H14ClN3O4S
CAS Number:
Molecular Weight:
367.81
Beilstein:
8176092
EC Number:
MDL number:
UNSPSC 코드:
51283701
PubChem Substance ID:
NACRES:
NA.85
추천 제품
양식
powder or crystals
solubility
soluble (slightly soluble in water, practically insoluble in methanol, ethanol)
항생제 활성 스펙트럼
Gram-negative bacteria
Gram-positive bacteria
동작 모드
cell wall synthesis | interferes
SMILES string
N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c3ccccc3
InChI
1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1
InChI key
QYIYFLOTGYLRGG-GPCCPHFNSA-N
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일반 설명
Chemical structure: ß-lactam
애플리케이션
Cefaclor has been used in the heterologous expression of AaOr7 and AaOr8 in Xenopus laevis oocytes.[1] It has also been used in cultures of isolated trigeminal ganglion (TG) and dorsal root ganglion (DRG) neurons.[2]
Cefaclor is used to study urinary tract, intra-abdominal, and Haemophilus influenzae infections [3][4][5]. It is used to study the mechanism of human renal organic anion and peptide transporters such as hOAT1, hPEPT1, and hPEPT2 and to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis [6].
생화학적/생리학적 작용
Cefaclor is a second generation cephalosporin with broad spectrum activity against Gram-negative and Gram-positive bacteria. It binds to penicillin-binding proteins and thereby inhibits the cell wall synthesis causing cell death.[3]
기타 정보
Keep container tightly closed in a dry and well-ventilated place. Slightly soluble in water, practically insoluble in methanol, chloroform and benzene.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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이미 열람한 고객
Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1
Kittaka H, et al.
The Journal of Physiology, 595(8), 2681-2698 (2017)
M Picard et al.
Antimicrobial agents and chemotherapy, 36(11), 2569-2572 (1992-11-01)
Cefaclor sustained its inhibitory activity against a beta-lactamase-producing strain of Haemophilus influenzae. Although a relatively high permeability coefficient was calculated for ampicillin compared with that calculated for cefaclor, the resulting periplasmic concentration of cefaclor was 5.7 times that of ampicillin.
Characterization of an enantioselective odorant receptor in the yellow fever mosquito Aedes aegypti
Bohbot J D and Dickens J C
Testing, 4(9), e7032-e7032 (2009)
Nikita B Ruparel et al.
Journal of endodontics, 38(10), 1372-1375 (2012-09-18)
Regenerative endodontic procedures are an alternative treatment for immature teeth with necrotic pulps. Typically, intracanal medicaments such as triple antibiotic paste (TAP) or double antibiotic paste (DAP) and calcium hydroxide (Ca[OH](2)) are used for disinfection. However, their effect on human
Basma Dabbagh et al.
Pediatric dentistry, 34(5), 414-417 (2012-12-06)
The purpose of this case series was to report on the use of a technique of revascularization for necrotic immature permanent teeth, several problems encountered, and solutions to those problems. Eighteen pulp revascularizations were performed in 2009 using the original
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