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Merck
모든 사진(1)

주요 문서

C3305

Sigma-Aldrich

Carbacyclin

≥90% (HPLC)

동의어(들):

6a-Carba-prostaglandin I2, Carbocyclic PGI2

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About This Item

실험식(Hill 표기법):
C21H34O4
CAS Number:
Molecular Weight:
350.49
MDL number:
UNSPSC 코드:
12352211
PubChem Substance ID:

분석

≥90% (HPLC)

저장 온도

−20°C

SMILES string

[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@]1([H])CC(\C2)=C\CCCC(O)=O

InChI

1S/C21H34O4/c1-2-3-4-8-17(22)10-11-18-19-13-15(7-5-6-9-21(24)25)12-16(19)14-20(18)23/h7,10-11,16-20,22-23H,2-6,8-9,12-14H2,1H3,(H,24,25)/b11-10+,15-7+/t16-,17-,18+,19-,20+/m0/s1

InChI key

XZFRIPGNUQRGPI-WBQKLGIQSA-N

유전자 정보

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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COX2-selective non-steroidal anti-inflammatory drugs (NSAIDs) cause selective apoptosis of renal medullary interstitial cells (RMIC) in vivo and reduce their ability to tolerate hypertonic stress in vitro. To determine the mechanism by which COX2 activity promotes RMIC viability, we examined the
R A Gupta et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(24), 13275-13280 (2000-11-23)
There is evidence from both genetic and pharmacologic studies to suggest that the cyclooxygenase-2 (COX-2) enzyme plays a causal role in the development of colorectal cancer. However, little is known about the identity or role of the eicosanoid receptor pathways
Charlotte C Jouvene et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(12), 13794-13807 (2019-10-08)
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K B Chow et al.
British journal of pharmacology, 134(7), 1375-1384 (2001-11-29)
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We have found that sebaceous epithelial cell (sebocyte) differentiation is induced by cognate ligand-agonists of either peroxisome proliferator-activated receptors (PPARs) or retinoid X receptors (RXRs). In this study, we tested the hypothesis that PPAR-RXR cooperation is used in sebocytes as

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