BM0012

BMS-191095 hydrochloride

≥98% (HPLC)

• 동의어(들): (3R,4S)-4-[(4-Chlorophenyl)(1H-imidazol-2-ylmethyl)amino]-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-carbonitrile monohydrochloride, (3R-trans)-4-[(4-Chlorophenyl)(1H-imidazol-2-ylmethyl)amino]-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-Benzopyran-6-carbonitrile monohydrochloride, BMS 191095 hydrochloride
• 실험식(Hill 표기법): C₂₂H₂₁ClN₄O₂ · HCl
• CAS Number: 166095-95-0
• Molecular Weight: 445.34
• MDL number: MFCD00953840
• UNSPSC 코드: 12352202
• PubChem Substance ID: 329774356
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: CC1(C)OC2=CC=C(C#N)C=C2[C@H](N(CC3=NC=CN3)C4=CC=C(Cl)C=C4)[C@H]1O.[H]Cl
• InChI: 1S/C22H21ClN4O2.ClH/c1-22(2)21(28)20(17-11-14(12-24)3-8-18(17)29-22)27(13-19-25-9-10-26-19)16-6-4-15(23)5-7-16;/h3-11,20-21,28H,13H2,1-2H3,(H,25,26);1H/t20-,21+;/m0./s1
• InChI key: TZLMTXNZECPICU-JUDYQFGCSA-N

설명

생화학적/생리학적 작용

BMS-191095 is a potent and selective mitochondrial ATP-sensitive K1 channel (KATP) channel opener devoid of peripheral vasodilating activity.

BMS-191095 is a potent and selective mitochondrial ATP-sensitive K1 channel (KATP) channel opener devoid of peripheral vasodilating activity. BMS-191095 improves postischemic recovery of function and reduced lactate dehydrogenase release in the isolated rat hearts.

특징 및 장점

BMS-191095 is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.

법적 정보

Sold for research purposes only under agreement from BMS.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable