AV45597
Anti-NR0B1 antibody produced in rabbit
IgG fraction of antiserum
동의어(들):
Anti-AHC, Anti-AHCH, Anti-AHX, Anti-DAX-1, Anti-DAX1, Anti-DSS, Anti-GTD, Anti-Nuclear receptor subfamily 0, group B, member 1
로그인조직 및 계약 가격 보기
크기 선택
100 μL
₩403,869
₩403,869
예상 입고일2025년 4월 07일세부사항
모든 사진(2)
크기 선택
보기 변경
100 μL
₩403,869
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩403,869
예상 입고일2025년 4월 07일세부사항
추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
IgG fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
52 kDa
종 반응성
human
농도
0.5 mg - 1 mg/mL
기술
immunohistochemistry: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... NR0B1(190)
면역원
Synthetic peptide directed towards the N terminal region of human NR0B1
애플리케이션
Anti-NR0B1 antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml.
생화학적/생리학적 작용
Nuclear receptor subfamily 0, group B, member 1 (NR0B1; DAX-1) is a DNA-binding protein that negatively regulates retinoic acid receptor-mediated transcription.[1] It is an antagonist to the protein Sry and functions as an anti-testis protein.[2] Mutations in gene encoding NR0B1 result in primary adrenal insufficiency or congenital adrenal hypoplasia in early childhood and hypogonadotropic hypogonadism.[3]
서열
Synthetic peptide located within the following region: TSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCC
물리적 형태
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Claudilene Battistin et al.
Arquivos brasileiros de endocrinologia e metabologia, 56(8), 496-500 (2013-01-09)
We report a case of adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HH) due to a novel DAX1 mutation. A 19-month-old boy with hyperpigmentation and failure to thrive came to our service for investigation. Three brothers of the patient had
Bryan W Teets et al.
Journal of cellular physiology, 227(4), 1501-1511 (2011-06-17)
Retinoic acid (RA) is critical for embryonic development and cellular differentiation. Previous work in our laboratory has shown that blocking the RA-dependent increase in pre-β cell leukemia transcription factors (PBX) mRNA and protein levels in P19 cells prevents endodermal and
X Yuan et al.
The Journal of biological chemistry, 276(49), 46647-46654 (2001-10-05)
This study investigated interactions between SRY, the Y chromosome encoded male sex determining factor, and the androgen receptor (AR). Coexpression of AR and SRY caused marked repression of AR transcriptional activity on a series of androgen-responsive reporter genes. Mammalian one-
Naoki Mine et al.
Molecular cancer therapeutics, 13(9), 2215-2225 (2014-07-24)
CBP501 is an anticancer drug candidate that was investigated in two randomized phase II clinical trials for patients with nonsquamous non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM). CBP501 has been shown to have two mechanisms of action
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