제품 AC-0062A은(는)귀하의 국가에서 현재 판매되지 않습니다. 고객지원팀으로 연락바랍니다.
추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
Ig fraction of antiserum
클론
monoclonal
양식
buffered aqueous solution
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200
동형
IgG
배송 상태
wet ice
저장 온도
2-8°C
시각화
(membrane/cytoplasm)
일반 설명
CD61, also known as GPIIIa and Integrin beta-3, is a glycoprotein encoded by the ITGB3 gene. CD61 heterodimerize with other cluster of differentiation molecules resulting in transmembrane integrins, facilitating cell to cell interactions and signal transduction. CD61 combines with CD41 to form platelet glycoprotein IIb/IIIa that serves as a receptor for fibrinogen and fibronectin. Platelet activation causes a conformational change in the glycoprotein to bind soluble fibrinogen to from a platelet plug. Alternative, CD61 can heterodimerize with CD51 to form Integrin alpha V beta 3, a receptor for vitronectin and von Willebrand factor. CD61 is expressed in the membrane and cytoplasm of platelets and megakaryocytes across diverse tissue types. Endothelium is also stained. Most cases of acute megakaryoblastic leukemia (AML M7) are positive for CD61.
품질
 IVD |  IVD |  IVD |  RUO |
물리적 형태
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
기타 정보
For a copy of the IFU and CofA contact [email protected]
For Technical Service please contact: 800-665-7284 or email: [email protected]
For Technical Service please contact: 800-665-7284 or email: [email protected]
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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