A9434

Ammonium chloride

for molecular biology, suitable for cell culture, ≥99.5%

• 동의어(들): Salmiac
• Linear Formula: NH₄Cl
• CAS Number: 12125-02-9
• Molecular Weight: 53.49
• Beilstein: 4371014
• EC Number: 235-186-4
• MDL number: MFCD00011420
• UNSPSC 코드: 12352302
• eCl@ss: 38050207
• PubChem Substance ID: 24891452
• NACRES: NA.31

속성

• Grade: Molecular Biology; for molecular biology
• vapor density: 1.9 (vs air)
• vapor pressure: 1 mmHg ( 160.4 °C)
• 분석: ≥99.5%
• 양식: powder or crystals
• 기술: cell culture | mammalian: suitable
• mp: 340 °C (subl.) (lit.)
• 음이온 미량물: phosphate (PO₄^3-): ≤2 ppm; sulfate (SO₄^2-): ≤20 ppm
• 양이온 미량물: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• 외래 활성: DNase, RNase, protease, none detected
• SMILES string: N.Cl
• InChI: 1S/ClH.H3N/h1H;1H3
• InChI key: NLXLAEXVIDQMFP-UHFFFAOYSA-N

설명

애플리케이션

Ammonium chloride has been used:

• as an inhibitor of endosome acidification in vero cells[1]
• as an autophagy inhibitor in vascular smooth muscle cell (VSMC)[2]
• in the depletion and lysis of erythrocytes in testis parenchyma homogenate[3]

생화학적/생리학적 작용

Ammonium chloride is one of the three principal components of the nitrogen cycle.[4] Ammonium chloride administration promotes creatinine and urea clearance[5] andinduces metabolic acidosis in mice.[6] Excess of ammonium chloride inhibits Kreb′s pathway in brain and depletes ATP in astrocytes.[7] Ammonium chloride inhibits acidification in the endosome-lysosome system.[8] Ammonium chloride is a hemolysing agent used for the lysis of erythrocytes.[9]

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H319
• 예방조치 성명서: P264 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves