A8344

Anti-ARC, C-Terminal antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-Apoptosis Repressor with CARD
• MDL number: MFCD02095862
• UNSPSC 코드: 12352203

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 22 kDa
• 종 반응성: human
• 기술: microarray: suitable; western blot: 1:1,000 using HeLa cell extract
• UniProt 수납 번호: O60936
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... NOL3(8996)

설명

일반 설명

ARC is part of the activity regulated cytoskeleton-associated protein family. It is involved in endocytosis of AMPA receptors and formation of long-term memory. It is found expressed in the cytoplasma of neuronal dendrites.

ARC protein contains an N-terminal CARD that has homology to the CARDs present in Apaf-1 and RAIDD. It binds to and inhibits the activity of caspase 8. It also binds to caspase 9 and to Ced-3. It inhibits apoptosis induced by death receptors that require caspase 8 activation.

Rabbit Anti-ARC, C-Terminal antibody binds to amino acids 191-208 of human ARC.

면역원

synthetic peptide corresponding to amino acids 191-208 of human ARC (apoptosis repressor with CARD).

애플리케이션

Rabbit Anti-ARC, C-Terminal antibody can be used for western blot (1:1,000) and microarray analyses.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.