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Merck
모든 사진(3)

문서

A7505

Sigma-Aldrich

1,4-Androstadiene-3,17-dione

동의어(들):

1-Dehydroandrostenedione, Androstadienedione

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About This Item

실험식(Hill 표기법):
C19H24O2
CAS Number:
Molecular Weight:
284.39
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.77

생물학적 소스

synthetic (organic)

분석

≥85% (HPLC)

형태

powder

약물 제어

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

chloroform: 50 mg/mL, clear, colorless to faintly yellow

저장 온도

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=O)CC[C@@]24[H]

InChI

1S/C19H24O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-16H,3-6,8,10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1

InChI key

LUJVUUWNAPIQQI-QAGGRKNESA-N

유전자 정보

human ... CYP19A1(1588)

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일반 설명

1,4-Androstadiene-3,17-dione is a 17-keto anabolic steroid.

생화학적/생리학적 작용

1,4-Androstadiene-3,17-dione is a prohormone that converts to an active steroid through the 17bHSD enzyme. 1,4-Androstadiene-3,17-dione is a metabolite of progesterone.
1,4-Androstadiene-3,17-dione is useful in forming pharmaceutically important steroids. Regio- and stereospecific hydroxylation of 1,4-androstadiene-3,17-dione increases its biological activity. Its derivative is also used to produce high-value bile acids. 1,4-Androstadiene-3,17-dione serves as a precursor for the synthesis of progesterone, testosterone, cortisol, estradiol, cortisone, prednisolone, and prednisone.

시험 성적서(COA)

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