A5730

Abz-SDK(Dnp)P-OH trifluoroacetate salt

≥91% (HPLC), lyophilized powder

• 동의어(들): o-Aminobenzoic acid-Ser-Asp-Lys(DNP)P-OH trifluoroacetate salt
• 실험식(Hill 표기법): C₃₁H₃₈N₈O₁₃ · xC₂HF₃O₂
• CAS Number: 1217465-57-0
• Molecular Weight: 730.68 (free base basis)
• MDL number: MFCD09753055
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24891013
• NACRES: NA.77

속성

• 분석: ≥91% (HPLC)
• 양식: lyophilized powder
• solubility: H₂O: freely soluble
• 저장 온도: 2-8°C
• SMILES string: OC(=O)C(F)(F)F.Nc1ccccc1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCNc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)C(=O)N3CCC[C@H]3C(O)=O
• InChI: 1S/C31H38N8O13.C2HF3O2/c32-19-7-2-1-6-18(19)27(43)36-23(16-40)29(45)35-22(15-26(41)42)28(44)34-21(30(46)37-13-5-9-24(37)31(47)48)8-3-4-12-33-20-11-10-17(38(49)50)14-25(20)39(51)52;3-2(4,5)1(6)7/h1-2,6-7,10-11,14,21-24,33,40H,3-5,8-9,12-13,15-16,32H2,(H,34,44)(H,35,45)(H,36,43)(H,41,42)(H,47,48);(H,6,7)/t21-,22-,23-,24-;/m0./s1
• InChI key: IFSUGURCQHMSJS-JPIABUGISA-N

설명

Amino Acid Sequence

Abz-Ser-Asp-Lys-DNP

애플리케이션

Abz-SDK(Dnp)P-OH trifluoroacetate is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that specifically binds to the N domain of ACE. Abz-SDK(Dnp)P-OH has been used to study tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells.

생화학적/생리학적 작용

Abz-SDK(Dnp)P-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the N domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).

특징 및 장점

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable