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Merck
모든 사진(3)

주요 문서

A5285

Sigma-Aldrich

Adenosine 5′-diphosphate monopotassium salt dihydrate

bacterial, ≥95%, powder

동의어(들):

Adenosine 5′-Diphosphate Potassium Salt, ADP

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크기 선택

100 MG
₩51,867
1 G
₩216,804
5 X 1 G
₩795,151

₩51,867


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

크기 선택

보기 변경
100 MG
₩51,867
1 G
₩216,804
5 X 1 G
₩795,151

About This Item

실험식(Hill 표기법):
C10H14KN5O10P2 · 2H2O
CAS Number:
Molecular Weight:
501.32
MDL number:
UNSPSC 코드:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.77

₩51,867


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

생물학적 소스

bacterial

분석

≥95%

양식

powder

저장 온도

−20°C

SMILES string

[O-]P(OP(OC[C@H]([C@@H](O)[C@H]1O)O[C@H]1N2C3=C(N=C2)C(N)=NC=N3)(O)=O)(O)=O.[K+]

InChI

1S/C10H15N5O10P2.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

InChI key

ZNCWUOPIJTUALR-MCDZGGTQSA-M

유전자 정보

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일반 설명

Adenosine diphosphate (ADP) is a crucial component for energy flow in living organisms. Its structure consists of a sugar backbone connected to adenine and two phosphate groups attached to the fifth carbon atom of the ribose sugar. ADP serves a precursor for ATP biosynthesis.[1] ADP acts as a weak platelet agonist, specifically targeting the P2Y receptor. However, ADP plays a vital role in platelet function by enhancing the effects of other platelet agonists and promoting the stability of platelet aggregates when released from platelet dense granules.[2]

애플리케이션

Adenosine 5′-diphosphate has been used to study the release, neuronal effects, and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD+) in the rat brain. Adenosine 5′-diphosphate has also been used to compare prasugrel versus clopidogrel antiplatelet therapy after acute coronary syndrome.
Adenosine 5′-diphosphate monopotassium salt dihydrate (ADP) has been used:
  • in titration to determine complex I-supported respiration in permeabilized muscle fibers[3]
  • in titrations to determine ADP-stimulated respiratory kinetics[4]
  • in the preparation of ADP solution for measuring mitochondrial respiration[5]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

James E Tcheng et al.
American journal of cardiovascular drugs : drugs, devices, and other interventions, 12(2), 83-91 (2012-02-10)
Antithrombotic therapy is imperative in the management of patients presenting with an acute coronary syndrome (ACS). The combination of antiplatelet therapy in conjunction with antithrombotic therapy has become the standard of care in improving the morbidity and mortality of patients
The Platelet P2 Receptors
Cattaneo M
Platelets (2013)
Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity
Hardee JP, et al.
Molecular Metabolism (2021)
Leonie Durnin et al.
The European journal of neuroscience, 35(3), 423-435 (2012-01-27)
Recent evidence supports an emerging role of β-nicotinamide adenine dinucleotide (β-NAD(+) ) as a novel neurotransmitter and neuromodulator in the peripheral nervous system -β-NAD(+) is released in nerve-smooth muscle preparations and adrenal chromaffin cells in a manner characteristic of a
Protocol for Measurement of Oxygen Consumption Rate In Situ in Permeabilized Cardiomyocytes
Gao M, et al.
STAR protocols (2020)

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