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Merck
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Key Documents

A4803

Sigma-Aldrich

Adenosine 5′-triphosphate γ-(1-[2-nitrophenyl]ethyl) ester sodium salt

≥95%

동의어(들):

“Caged” ATP

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About This Item

실험식(Hill 표기법):
C18H21N6Na2O15P3
CAS Number:
Molecular Weight:
700.29
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:

분석

≥95%

형태

powder

저장 온도

−20°C

SMILES string

[Na+].[Na+].CC(OP([O-])(=O)OP([O-])(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23)c4ccccc4[N+]([O-])=O

InChI

1S/C18H23N6O15P3.2Na/c1-9(10-4-2-3-5-11(10)24(27)28)37-41(31,32)39-42(33,34)38-40(29,30)35-6-12-14(25)15(26)18(36-12)23-8-22-13-16(19)20-7-21-17(13)23;;/h2-5,7-9,12,14-15,18,25-26H,6H2,1H3,(H,29,30)(H,31,32)(H,33,34)(H2,19,20,21);;/q;2*+1/p-2/t9?,12-,14-,15-,18-;;/m1../s1

InChI key

DWGOHIKVVKFGGU-DZHDPEGHSA-L

애플리케이션

Adenosine 5′-triphosphate γ-(1-[2-nitrophenyl]ethyl) ester (“Caged” ATP) is used as a photolyzing substrate of luciferase-mediated firefly bioluminescence and other ATP-dependent photolytic processes. Caged ATP has also been used to study the dynamics of ATP-driven linear molecular motors such as myosin Va.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Katsuyuki Shiroguchi et al.
PLoS biology, 9(4), e1001031-e1001031 (2011-05-03)
Myosins are ATP-driven linear molecular motors that work as cellular force generators, transporters, and force sensors. These functions are driven by large-scale nucleotide-dependent conformational changes, termed "strokes"; the "power stroke" is the force-generating swinging of the myosin light chain-binding "neck"
Takeshi Kageyama et al.
Photochemistry and photobiology, 87(3), 653-658 (2011-01-07)
The reaction process of firefly bioluminescence was studied by photolyzing caged-ATP to adenosine triphosphate (ATP) within 100 ms. The intensity of luminescence increases markedly to reach a maximum within 1 s, maintains almost the same intensity up to 5 s
Christian Völlmecke et al.
The FEBS journal, 276(21), 6172-6186 (2009-09-29)
The mechanism of ATP hydrolysis of a shortened variant of the heavy metal-translocating P-type ATPase CopB of Sulfolobus solfataricus was studied. The catalytic fragment, named CopB-B, comprises the nucleotide binding and phosphorylation domains. We demonstrated stoichiometric high-affinity binding of one
J A McCray et al.
Proceedings of the National Academy of Sciences of the United States of America, 77(12), 7237-7241 (1980-12-01)
2-Nitrobenzyl derivatives have been used for several years as photolabile protecting groups in synthetic organic chemistry. Recently, P3-1-(2-nitro phenylethyladenosine 5'-triphosphate "caged ATP" was synthesized and its photolysis was shown to generate ATP in situ. This and related reactions have great
Savas Tasoglu et al.
Advanced materials (Deerfield Beach, Fla.), 27(26), 3901-3908 (2015-06-11)
A simple, yet powerful magnetic-levitation-based device is reported for real-time, label-free separation, as well as high-resolution monitoring of cell populations based on their unique magnetic and density signatures. This method allows a wide variety of cellular processes to be studied

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