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Merck
모든 사진(4)

문서

A4685

Sigma-Aldrich

Luminol sodium salt

luminescent, ≥98% (titration), powder and chunks

동의어(들):

3-Aminophthalhydrazide, 5-Amino-2,3-dihydro-1,4-phthalazinedione

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About This Item

Linear Formula:
C8H6N3O2Na
CAS Number:
Molecular Weight:
199.14
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.83

product name

Luminol sodium salt,

분석

≥98% (titration)

형태

powder and chunks

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to faint red

SMILES string

O=C1NN([Na])C(C2=CC=CC(N)=C21)=O

InChI

1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,(H4,9,10,11,12,13);/q;+1/p-1

InChI key

RVJVDCVIJCBUTH-UHFFFAOYSA-M

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애플리케이션

Luminol sodium salt has been used:

  • as a component of MEBSS buffer in a bioluminescence assay to detect peroxidase activity in whole blood samples
  • to study protein interaction in whole-cell lysates by immunoprecipitation
  • for in vitro reactive oxygen species (ROS) quantification in CD45+ and CD45− cells

생화학적/생리학적 작용

Luminol is a redox-sensitive chemiluminescent compound. It emits blue luminescence when the basic aqueous solution of luminol having oxygen atoms come in contact with oxidizing agents like potassium ferricyanide. It is highly stable and is applicable in various fields such as analytical chemistry, metallurgy, biochemistry, and forensics for detecting reactive species. Luminol has the potential to detect defects in neutrophils ex vivo during oxidative metabolism defects such as chronic granulomatous disease and myeloperoxidase deficiency.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Chemiluminescence detection in analytical chemistry
Lancaster, J. Steven
Endeavour, 16, 194-194 (1992)
Yantu Zhang et al.
Journal of chromatography. A, 1154(1-2), 260-268 (2007-04-24)
A novel method was developed for the simultaneous determination of glucocorticoid residues such as triamcinolone (TR), prednisolone (PR), hydrocortisone (HC), cortisone (CO), methylprednisolone (MP), dexamethasone (DE) and triamcinolone acetonide (TA) by high-performance liquid chromatography (HPLC) coupled with chemiluminescence (CL) detection.
New Developments in Chemiluminescence Research
Gill, Steven, K.
Aldrichimica Acta, 16, 59-59 (1983)
Opioids prevent regeneration in adult mammals through inhibition of ROS production
Elodie L, et al.
Scientific Reports, 8(1) (2018)
Chemilunimescence of luminol: The chemcial reaction
White E H, et al.
ACS Chemical Biology, 86(5), 940-941 (1964)

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