모든 사진(5)
About This Item
실험식(Hill 표기법):
C5H5N5 · HNO3
CAS Number:
Molecular Weight:
198.14
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:
NACRES:
NA.51
추천 제품
생물학적 소스
synthetic
Quality Level
분석
≥99%
형태
powder
solubility
water: 50 mg/mL, clear, faintly to light yellow
SMILES string
O[N+]([O-])=O.Nc1ncc2[nH]cnc2n1
InChI
1S/C5H5N5.HNO3/c6-5-7-1-3-4(10-5)9-2-8-3;2-1(3)4/h1-2H,(H3,6,7,8,9,10);(H,2,3,4)
InChI key
PGDNOZBGABWZLD-UHFFFAOYSA-N
애플리케이션
2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR).
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Yasumi Endoh et al.
Journal of immunology (Baltimore, Md. : 1950), 182(4), 2258-2268 (2009-02-10)
The S100 calcium-binding proteins S100A8 and S100A9 are elevated systemically in patients with viral infections. The S100A8-S100A9 complex facilitated viral replication in human CD4(+) T lymphocytes latently infected with HIV-1- and S100A8-induced HIV-1 transcriptional activity. Mechanisms inducing the S100 genes
Michael E Lindquist et al.
Virology, 413(1), 103-110 (2011-03-08)
We performed experiments to determine the effect of PKR activation on respiratory syncytial virus (RSV) replication. We first determined that RSV infection activates PKR which induces the phosphorylation of eIF2α, resulting in the formation of host stress granules. We used
Junpei Teramachi et al.
Experimental cell research, 316(19), 3254-3262 (2010-08-24)
Double-stranded RNA-dependent protein kinase (PKR) plays a critical role in antiviral defence of the host cells. PKR is also involved in cell cycle progression, cell proliferation, cell differentiation, tumorigenesis, and apoptosis. We previously reported that PKR is required for differentiation
Renata M S Pereira et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(2), 617-626 (2009-10-09)
The evolution of Leishmania infection depends on the balance between microbicidal and suppressor macrophage functions. Double-stranded RNA (dsRNA)-activated protein kinase R (PKR), a classic antiviral protein, is able to regulate a number of signaling pathways and macrophage functions. We investigated
Chen-Hsuan Wang et al.
Brain research bulletin, 79(3-4), 169-176 (2009-05-12)
Molecules involved in self-protection of neurons against glucose/oxygen/serum deprivation (GOSD) were investigated. Trypan blue dye exclusion assay, Western blotting, ELISA, cytokine antibody array and chemical blocking assay were applied in the study. Results showed that early induction (at 6h of
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