A0987

n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate

≥98% (HPLC)

• 동의어(들): Cytosporone A n-amyl ester, compound 10i
• 실험식(Hill 표기법): C₂₂H₃₄O₅
• CAS Number: 1257228-26-4
• Molecular Weight: 378.50
• MDL number: MFCD18632550
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329770645
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white
• solubility: DMSO: >65 mg/mL
• 저장 온도: 2-8°C
• SMILES string: CCCCCCCCC(=O)c1c(O)cc(O)cc1CC(=O)OCCCCC
• InChI: 1S/C22H34O5/c1-3-5-7-8-9-10-12-19(24)22-17(14-18(23)16-20(22)25)15-21(26)27-13-11-6-4-2/h14,16,23,25H,3-13,15H2,1-2H3
• InChI key: FCKDHZVFIMRCNM-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist.

n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus.

특징 및 장점

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable