54297
(−)-α-Conidendrin
≥95.0% (HPLC)
동의어(들):
(3aR,4S,9aR)-3a,4,9,9a-Tetrahydro-6-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methoxynaphtho[2,3-c]furan-1(3H)-one, (3aR,4S,9aR)-6-Hydroxy-4-(4-hydroxy-3-methoxy-phenyl)-7-methoxy-3a,4,9,9a-tetrahydro-3H-naphtho[2,3-c]furan-1-one, NSC 4586, Tsugalactone
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C20H20O6
CAS Number:
Molecular Weight:
356.37
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
추천 제품
분석
≥95.0% (HPLC)
SMILES string
COc1cc2C[C@@H]3[C@H](COC3=O)[C@@H](c4ccc(O)c(OC)c4)c2cc1O
InChI
1S/C20H20O6/c1-24-17-6-10(3-4-15(17)21)19-12-8-16(22)18(25-2)7-11(12)5-13-14(19)9-26-20(13)23/h3-4,6-8,13-14,19,21-22H,5,9H2,1-2H3/t13-,14+,19+/m1/s1
InChI key
CAYMSCGTKZIVTN-TYILLQQXSA-N
애플리케이션
α-conidendrin is a plant derived lignan that may be used as a source or reference compound to study bacteria that degrade plant lignans. α-conidendrin may be used as a starting material for the synthesis of sikkimotoxin derivatives and cytotoxic metabolites.
포장
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Robert T LaLonde et al.
Journal of natural products, 67(4), 697-699 (2004-04-24)
Oxidation of alpha-conidendrin (3) by Fremy's salt favored formation of an o-quinone (4) at the pendant aromatic ring as opposed to the fused aromatic ring. Quinone reduction and phenolic methylation, followed by lactone reduction, and subsequent oxidation by dichlorodicyanoquinone produced
Annika I Smeds et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 816(1-2), 87-97 (2005-01-25)
Ten potential lignan metabolites were quantified in rat urine extracts using liquid chromatography-tandem mass spectrometry. The rats were orally administered with the plant lignans 7-hydroxymatairesinol, matairesinol, lariciresinol or secoisolariciresinol, or with the mammalian lignan enterolactone. The samples were enzymatically hydrolysed
Yimin Hu et al.
Chemistry, an Asian journal, 5(2), 309-314 (2009-12-31)
An efficient domino cyclization method for the construction of aza-podophyllotoxin/aza-conidendrin derivatives has been established. Reactions of different dienes with aryl halides in the presence of a palladium catalytic system produced different kinds of podophyllotoxin derivatives through a highly regioselective C-H
A Dantzig et al.
Journal of medicinal chemistry, 44(2), 180-185 (2001-02-15)
Derivatives of alpha-conidendrin, podophyllotoxin, and sikkimotoxin were prepared to evaluate the cytotoxic contributions of C-4 configuration and pendant and fused arene substitutions. Dimethyl-alpha-conidendryl alcohol (5), 9-deoxypodophyllol (6), and 9-deoxysikkimol (17) were dehydrated to their respective oxolane derivatives 4, 3, and
Joshua Fischer et al.
Organic letters, 6(9), 1345-1348 (2004-04-23)
[reaction: see text] Total syntheses of seven biologically important lignan natural products, including (-)-arctigenin, (-)-matairesinol, and (-)-alpha-conidendrin, by way of a highly stereoselective domino radical sequence is presented. The reported stereochemistry of the natural product 7-hydroxyarctigenin is shown to be
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