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Merck
모든 사진(2)

문서

540-05A

Sigma-Aldrich

Human Lung Microvascular Endothelial Cells: HLMVEC, adult

동의어(들):

HLMVEC, HLMVEC cells

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About This Item

UNSPSC 코드:
41106514
NACRES:
NA.81

생물학적 소스

human lung (normal)

Quality Level

포장

pkg of 500,000 cells

제조업체/상표

Cell Applications, Inc

성장 모드

Adherent

핵형

2n = 46

형태학

Endothelial

기술

cell culture | mammalian: suitable

관련 질환(들)

metastasis

배송 상태

dry ice

저장 온도

−196°C

일반 설명

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

The pulmonary vasculature is of great physiological/pathological significance. It is now recognized to be a tissue composed of metabolically active, functionally responsive cells, that interact with circulating substrates and regulate the composition of systemic arterial blood, affect target organ functions, and contribute to thrombosis, hemostasis and immune reactions, as well as tumor metastasis. Human Lung Microvascular Endothelial Cells (HLMVEC) provide a useful tool for studying various aspects of pathology and biology of the pulmonary microvasculature in vitro.

HLMVEC have been used to elucidate the therapeutic effects of Angiotensin I-converting enzyme (ACE) inhibitors, and the results revealed that they provide an additional benefit to patients by activating bradykinin B1 receptor leading to prolonged nitric oxide (NO) production in endothelial cells and inhibition of PKCε (Ignjatovic, 2004; Stanisavljevic, 2006).

세포주 기원

Lungs

애플리케이션

lung physiology, metabolism, regulate blood composition, hemostasis, immune reactions, therapeutic effects, leukocyte migration,

성분

Cell Basal Medium containing 10% FBS & 10% DMSO

제조 메모

  • 3rd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 15 doublings

계대배양 정규 작업

Please refer to the HLMVEC Culture Protocol.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Huiyuan Yan et al.
Experimental and therapeutic medicine, 26(1), 319-319 (2023-06-05)
Acute lung injury (ALI) is associated with increased lung inflammation and lung permeability. The present study aimed to determine the role of inactive rhomboid-like protein 2 (iRHOM2) in ALI in lipopolysaccharide (LPS)-induced pulmonary microvascular endothelial cell model. Human pulmonary microvascular

프로토콜

Technical information for working with human lung microvascular endothelial cells including thawing, subculturing and cryopreservation

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