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Merck
모든 사진(1)

주요 문서

282M-9

Sigma-Aldrich

HMB-45 (HMB-45) Mouse Monoclonal Antibody

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41
가격 및 재고 정보를 현재 이용할 수 없음

생물학적 소스

mouse

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

HMB-45, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

양식

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (282M-94)
vial of 0.5 mL concentrate (282M-95)
bottle of 1.0 mL predilute (282M-97)
vial of 1.0 mL concentrate (282M-96)
bottle of 7.0 mL predilute (282M-98)

제조업체/상표

Cell Marque®

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

동형

IgG1κ

제어

melanoma

배송 상태

wet ice

저장 온도

2-8°C

시각화

cytoplasmic

일반 설명

Anti-HMB45 is a useful melanoma immunohistochemical marker that reacts with antigenspresent on immature melanosomes. Anti-HMB45 is useful for identifying amelanoticmelanoma from other neoplastic lesions with similar morphology.

품질


IVD

IVD

IVD

RUO

결합

HMB-45 Positive Control Slides, Product No. 282S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: [email protected]

법적 정보

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

M R Wick et al.
Archives of pathology & laboratory medicine, 112(6), 616-620 (1988-06-01)
The efficacy of two new monoclonal antibodies with cell lineage-restricted reactivity (HMB-45 [melanocytes] and anti-synaptophysin [neuroepithelial cells]) was compared with that of "traditional" antibody panels in the delineation of malignant melanoma (MM) of the sinonasal region, nasopharyngeal carcinoma (NPC), and
Helene Nortvig Abrahamsen et al.
Cancer, 100(8), 1683-1691 (2004-04-10)
The optimal technique for sentinel lymph node (SN) assessment in patients with melanoma is controversial. Molecular analysis (reverse transcriptase-polymerase chain reaction) detects significantly greater numbers of SNs with suspected micrometastases (up to 71%) than does routine histopathology (approximately 20%). The
L Weiss et al.
The Journal of pathology, 150(3), 195-203 (1986-11-01)
The sequence of events in haematogenous metastasis from colonic carcinoma was analysed, using 1541 necropsy reports from 16 centres. The findings are consistent with the cascade hypothesis that metastases develop in discrete steps, first in the liver, next in the
An assessment of a melanoma-specific antibody (HMB-45) and other immunohistochemical markers of malignant in paraffin-embedded tissue.
AS-Y Leong, et al.
Surgical Pathology, 2, 137-145 (1989)
A M Gown et al.
The American journal of pathology, 123(2), 195-203 (1986-05-01)
The authors have generated monoclonal antibodies to an extract of melanoma. When tested on a variety of fixed, embedded sections of malignant tumors, one antibody (HMB-45) reacted with 60 of 62 melanomas and none of 168 nonmelanomas (carcinomas, lymphomas, and

문서

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

관련 콘텐츠

Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

진단 면역조직화학 개요는 현대 임상 병리학에서 암 진단과 감염 질환을 탐지하는 진단 면역조직화학의 중요성을 강조합니다.

질문

후기

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활성 필터

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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