27689

Concanamycin A

from Streptomyces sp., ≥80% (HPLC)

• 동의어(들): Folimycin
• 실험식(Hill 표기법): C₄₆H₇₅NO₁₄
• CAS Number: 80890-47-7
• Molecular Weight: 866.09
• Beilstein: 3560277
• MDL number: MFCD00210037
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329753012
• NACRES: NA.25

속성

• 생물학적 소스: Streptomyces sp.
• 분석: ≥80% (HPLC)
• 형태: solid
• 항생제 활성 스펙트럼: viruses
• 동작 모드: enzyme | inhibits
• 저장 온도: −20°C
• SMILES string: CCC1C(O)C(C)C\C(C)=C\C=C\C(OC)C(OC(=O)\C(OC)=C\C(C)=C\C(C)C1O)C(C)C(O)C(C)[C@]2(O)C[C@@H](O[C@H]3C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O3)[C@H](C)C(O2)\C=C\C
• InChI: 1S/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22-23H2,1-12H3,(H2,47,53)/b16-13+,18-15+,24-17+,25-20+,36-21-/t26?,27?,28-,29?,30?,31-,32?,33-,34?,35?,37-,38+,39?,40?,41?,42?,43-,46+/m1/s1
• InChI key: DJZCTUVALDDONK-LWLXYWDNSA-N

설명

일반 설명

Chemical structure: macrolide

애플리케이션

Concanamycin A has been used as an inhibitor of the perforin pathway.

기타 정보

Characterization of concanamycins A, B and C; Selective inhibitor of the vacuolar proton-ATPase.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330,H319
• 예방조치 성명서: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Eye Irrit. 2
• Storage Class Code: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges