27555

Cloxacillin sodium salt

≥95.0% (HPLC)

• 동의어(들): 3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt, Syntarpen sodium salt
• 실험식(Hill 표기법): C₁₉H₁₇ClN₃NaO₅S
• CAS Number: 642-78-4
• Molecular Weight: 457.86
• Beilstein: 4103180
• EC Number: 211-390-9
• MDL number: MFCD00063568
• UNSPSC 코드: 51102829
• PubChem Substance ID: 57648259
• NACRES: NA.85

속성

• 생물학적 소스: semisynthetic
• 분석: ≥95.0% (HPLC)
• 형태: powder or crystals
• 불순물: ≤5% Total impurities (anhydrous)
• 색상: white to off-white
• 항생제 활성 스펙트럼: Gram-positive bacteria
• 동작 모드: cell wall synthesis | interferes
• 저장 온도: 2-8°C
• SMILES string: [Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
• InChI: 1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1
• InChI key: SCLZRKVZRBKZCR-SLINCCQESA-M

설명

일반 설명

Chemical structure: ß-lactam

애플리케이션

Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria.

생화학적/생리학적 작용

Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.

기타 정보

Keep container tightly closed in a dry and well-ventilated place.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)