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Merck
모든 사진(1)

문서

243M-1

Sigma-Aldrich

Desmin (D33) Mouse Monoclonal Antibody

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

D33, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

형태

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (243M-14)
vial of 0.5 mL concentrate (243M-15)
bottle of 1.0 mL predilute (243M-17)
vial of 1.0 mL concentrate (243M-16)
bottle of 7.0 mL predilute (243M-18)

제조업체/상표

Cell Marque

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

동형

IgG1κ

제어

muscle

배송 상태

wet ice

저장 온도

2-8°C

시각화

cytoplasmic

유전자 정보

human ... DES(1674)

일반 설명

Anti-desmin detects a protein that is expressed by cells of normal smooth, skeletal, and cardiac muscles. The light microscope has suggested that desmin is primarily located at or near the periphery of Z lines in striated muscle fibrils. In smooth muscle, desmin interconnects cytoplasmic dense bodies with membrane bound dense plaques. Anti-desmin reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. This antibody is used to demonstrate the myogenic components/derivation of tumors. Desmin can also be present in myofibroblasts and be focally positive in desmoid fibromatosis.

품질


IVD

IVD

IVD

RUO

결합

Desmin Positive Control Slides, Product No. 243S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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문서 라이브러리 방문

M Altmannsberger et al.
The American journal of pathology, 118(1), 85-95 (1985-01-01)
Putative human rhabdomyosarcoma (RMS) has been divided into two groups according to desmin content. Twenty-five tumors with histologic features consistent with but not necessarily sufficient to prove a diagnosis of RMS were desmin-positive. More than 95% of the tumor cells
Umio Yamaguchi et al.
Virchows Archiv : an international journal of pathology, 445(2), 142-150 (2004-07-03)
To confirm the usefulness of an immunohistochemical panel of antibodies for KIT (c-kit/CD117), CD34, desmin, smooth-muscle actin (SMA), h-caldesmon (HCD), S-100 protein, neuron-specific enolase (NSE), and beta-catenin, 297 mesenchymal and peripheral nerve-sheath tumors of the gastrointestinal tract and intra-abdominal locations
E Debus et al.
The EMBO journal, 2(12), 2305-2312 (1983-01-01)
A set of monoclonal antibodies to desmin has been isolated from a fusion of mouse myeloma cells with spleen cells from mice immunized with purified porcine desmin. Eleven group I antibodies recognized desmin in the immune blot, and using defined

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