추천 제품
생물학적 소스
mouse
Quality Level
100
500
결합
unconjugated
항체 형태
culture supernatant
항체 생산 유형
primary antibodies
클론
CIV22, monoclonal
설명
For In Vitro Diagnostic Use in Select Regions (See Chart)
양식
buffered aqueous solution
종 반응성
human
포장
vial of 0.1 mL concentrate (239M-14)
vial of 0.5 mL concentrate (239M-15)
bottle of 1.0 mL predilute (239M-17)
vial of 1.0 mL concentrate (239M-16)
bottle of 7.0 mL predilute (239M-18)
제조업체/상표
Cell Marque®
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
동형
IgG1
제어
lung
배송 상태
wet ice
저장 온도
2-8°C
유전자 정보
human ... COL4A1(1282)
일반 설명
Collagen Type IV is the major component of the basal lamina so antibodies to this molecule confirm its presence and reveal the morphological appearance of the structure. Normal tissue stains with this antibody in a fashion consistent with the sites of mesenchymal elements and epithelial basal laminae. Anti-Collagen IV can also be useful in the classification of soft tissue tumors: schwannomas and leiomyomas. Their well-differentiated, malignant counterparts usually immunoreact with this antibody. The vascular nature of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma can be revealed by this antibody with greater reliability than non-specific stains (e.g. silver reticulum)
품질
 IVD |  IVD |  IVD |  RUO |
결합
Collagen Type IV Positive Control Slides, Product No. 239S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
물리적 형태
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
제조 메모
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
기타 정보
For Technical Service please contact: 800-665-7284 or email: [email protected]
법적 정보
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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시험 성적서(COA)
Lot/Batch Number
S Damiani et al.
Virchows Archiv : an international journal of pathology, 434(3), 227-234 (1999-04-06)
A retrospective study was made of 38 selected brest tumours with a poorly differentiated in situ duct component. These were classified on haematoxylin and eosin (H&E) as ductal carcinoma in situ (DCIS; 10 cases), DCIS with invasion (17 cases) and
J P McArdle et al.
International journal of cancer, 34(5), 633-638 (1984-11-15)
The basal lamina in a variety of metastatic tumours in brain was assessed with an antibody to type-IV collagen and the indirect immunoperoxidase technique. The antibody was raised in rabbits against type-IV collagen isolated from human placental tissue. Basal lamina
S H Barsky et al.
The American journal of surgical pathology, 7(7), 667-677 (1983-10-01)
A new method has been developed for identifying blood vessel capillaries and distinguishing them from lymphatic capillaries. Highly purified antibodies to two ubiquitous components of basement membrane--Type IV collagen and laminin--were applied to fresh-frozen and formalin-fixed tissue sections rich in
P De Iorio et al.
Anticancer research, 21(2B), 1395-1399 (2001-06-09)
The prognostic variability in breast cancer patients prompted the authors to investigate specific biological markers for the identification of high-risk breast cancer groups. In the present study, attention was focused on the interaction between tumor cells and the extracellular matrix
M Määttä et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 49(6), 711-726 (2001-05-25)
Laminins (Ln), together with Type IV collagen and nidogen-1, form the structural integrity of the basement membranes (BM). In this study we used immunohistochemistry to show the distribution of laminin chains alpha1, alpha3, alpha5, beta1, beta2, beta3, gamma1, gamma2, as
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