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주요 문서

COO/COA

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12266

N-[4-(2-Benzimidazolyl)phenyl]maleimide

Name: <I>N</I>-[4-(2-Benzimidazolyl)phenyl]maleimide
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

동의어(들):

BIPM

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About This Item

실험식(Hill 표기법):

C₁₇H₁₁N₃O₂

CAS Number:

27030-97-3

Molecular Weight:

289.29

Beilstein:

755407

EC Number:

248-173-3

MDL number:

MFCD00042767

UNSPSC 코드:

12352200

PubChem Substance ID:

57646978

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제품 라인

BioReagent

분석

≥98.0% (HPLC)

양식

solid

solubility

H₂O: soluble
acetone: soluble

형광

λ_ex 315 nm; λ_em 365 nm (after derivatization with 2-mercaptoethanol)

적합성

suitable for fluorescence

SMILES string

O=C1C=CC(=O)N1c2ccc(cc2)-c3nc4ccccc4[nH]3

InChI

1S/C17H11N3O2/c21-15-9-10-16(22)20(15)12-7-5-11(6-8-12)17-18-13-3-1-2-4-14(13)19-17/h1-10H,(H,18,19)

InChI key

NZDOXVCRXDAVII-UHFFFAOYSA-N

기타 정보

Fluorescent probe in proteins, used for microfluorometry of thiol compounds (detection limit: 10^-6 m thiol conc.)[1]; Review[2][3]

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Stopped flow measurement of conformational change induced by phosphorylation in (Na+,K+)-ATPase modified with N-[p-(2-benzimidazolyl)phenyl]maleimide.

K Taniguchi et al.

The Journal of biological chemistry, 258(11), 6927-6931 (1983-06-10)

The addition of ATP to (Na+,K+)-ATPase (EC 3.6.1.3) of pig kidney modified with N-[p-(2-benzimidazolyl)phenyl]maleimide induced three different modes of fluorescence change: positive, biphasic, and negative, which were observed, respectively, in the presence of Mg2+ with 16 or 160, 320 or

A Printable Device for Measuring Clarity and Colour in Lake and Nearshore Waters.

Robert J W Brewin et al.

Sensors (Basel, Switzerland), 19(4) (2019-03-01)

Two expanding areas of science and technology are citizen science and three-dimensional (3D) printing. Citizen science has a proven capability to generate reliable data and contribute to unexpected scientific discovery. It can put science into the hands of the citizens

Fluorescent thiol reagents. V. Microfluorometry of thiol compounds with a fluorescent-labeled maleimide.

T Sekine et al.

Analytical biochemistry, 48(2), 557-568 (1972-08-01)

Effect of peptide bond splitting on ouabain sensitive conformational changes in Na+,K+-ATPase treated with N-[p-(2-benzimidazolyl)phenyl]maleimide.

S Inoue et al.

Japanese journal of pharmacology, 43(1), 107-111 (1987-01-01)

Trypsin treatment of N-[p-(2-benzimidazolyl)phenyl]maleimide modified enzyme caused a marked reduction in Na+,K+-ATPase activity and in the amount of the alpha-chain, which contains the phosphorylation and ouabain binding sites. However, these preparations retained nearly 90% of the ouabain binding capacity and

Conformational change of sodium- and potassium-dependent adenosine triphosphatase. Conformational evidence for the Post-Albers mechanism in Na+- and K+-dependent hydrolysis of ATP.

K Taniguchi et al.

The Journal of biological chemistry, 259(24), 15228-15233 (1984-12-25)

The addition of ATP with K+ to pig kidney Na+,K+-ATPase (EC 3.6.1.3) modified with a sulfhydryl fluorescent reagent N-[p-(2-benzimidazolyl)phenyl]maleimide induced a transient decrease (t 1/2 = 0.01 s) in the fluorescence in the presence of Mg2+ with 0.64 M Na+

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