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Merck
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문서

PHR1566

Supelco

D5 Cyclomethicone

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Decamethylcyclopentasiloxane

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About This Item

실험식(Hill 표기법):
C10H30O5Si5
CAS Number:
Molecular Weight:
370.77
Beilstein:
1800166
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1154809

API family

cyclomethicone

CofA

current certificate can be downloaded

포장

pkg of 500 mg

기술

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.396 (lit.)

bp

90 °C/10 mmHg (lit.)

density

0.958 g/mL at 25 °C (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1

InChI

1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3

InChI key

XMSXQFUHVRWGNA-UHFFFAOYSA-N

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일반 설명

D5 Cyclomethicone is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom. It is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

애플리케이션

D5 Cyclomethicone may be used as a pharmaceutical reference standard for the determination of the analyte in personal care formulations by gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAC2966 in the slot below. This is an example certificate only and may not be the lot that you receive.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

163.4 °F - closed cup

Flash Point (°C)

73 °C - closed cup


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시험 성적서(COA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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문서 라이브러리 방문

Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane
Johnson Jr, et al.
International Journal of Toxicology, 30, 149S-227S (2011)
Sensitive method for quantification of octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5) in end-exhaled air by thermal desorption gas chromatography mass spectrometry
Biesterbos JWH, et al.
Analytical Chemistry, 86(12), 5794-5799 (2014)
Determination of cyclic volatile methylsiloxanes in personal care products by gas chromatography
Brothers Jr HM, et al.
International Journal of Cosmetic Science, 39(6), 580-588 (2017)
Seon Ju Yeo et al.
Soft matter, 11(8), 1582-1588 (2015-01-17)
Colloidal photonic crystals (CPCs) provide a convenient way to generate structural colour with high stability against degradation under environmental factors. For a number of applications including flexible electronic and energy devices, it is important to generate flexible structural colour that

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