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Merck
모든 사진(3)

문서

P4722

Sigma-Aldrich

Pyridoxine hydrochloride

meets USP testing specifications

동의어(들):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

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About This Item

실험식(Hill 표기법):
C8H11NO3 · HCl
CAS Number:
Molecular Weight:
205.64
Beilstein:
3632435
EC Number:
MDL number:
UNSPSC 코드:
12352205
eCl@ss:
34058008
PubChem Substance ID:
NACRES:
NA.21

생물학적 소스

synthetic (organic)

Quality Level

Agency

USP/NF
meets USP testing specifications

분석

98.0-102.0% dry basis

형태

powder

색상

white

mp

214-215 °C (lit.)

응용 분야

pharmaceutical (small molecule)

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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일반 설명

Vitamin B group is water-soluble and exists in six forms namely the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. The food sources of vitamin B6 include grains, nuts, fruits, vegetables and meat.

애플리케이션

Pyridoxine hydrochloride has been used to test its neuroprotective functionality in traumatic brain injury (TBI) rats. It has also been used as a reference standard to quantify vitamin B6 in feed and digesta samples using high-performance liquid chromatography(HPLC).

생화학적/생리학적 작용

Pyridoxine plays a key role in metabolism both carbohydrates and amino acids. It supports brain development and its deficiency levels may lead to depletion of γ-aminobutyric acid (GABA) levels. Pyridoxine catalyzes the neurotransmitter biosynthesis like dopamine and serotonin. Pyridoxine in excess or deficient may lead to neuropathy.

픽토그램

Corrosion

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Nutritional neuropathies
Hammond N, et al.
Neurologic Clinics, 31(2), 477-477 (2013)
B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin
Calderon-Ospina CA, et al.
CNS Neuroscience & Therapeutics (2019)
Pyridoxine administration improves behavioral and anatomical outcome after unilateral contusion injury in the rat
Kuypers NJ and Hoane MR
Journal of Neurotrauma, 27(7), 1275-1282 (2010)
Effects of forage family on apparent ruminal synthesis of B vitamins in lactating dairy cows
Castagnino DS, et al.
Journal of Dairy Science, 99(3), 1884-1894 (2016)
Determination of vitamin B6 (pyridoxine) in pharmaceutical preparations by cyclic voltammetry at a copper (II) hexacyanoferrate (III) modified carbon paste electrode
Teixeira MFS, et al.
Journal of the Brazilian Chemical Society, 14(2), 316-321 (2003)

문서

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

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