추천 제품
Grade
pharmaceutical primary standard
API family
pentoxifylline
제조업체/상표
EDQM
응용 분야
pharmaceutical (small molecule)
형식
neat
SMILES string
CN1C=NC2C1C(=O)N(CCCCC(C)=O)C(=O)N2C
InChI
1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8,10-11H,4-7H2,1-3H3
InChI key
MQGNNJQTNFHNHK-UHFFFAOYSA-N
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일반 설명
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
애플리케이션
Pentoxifylline EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
생화학적/생리학적 작용
Phosphodiesterase inhibitor; inhibits synthesis of tumor necrosis factor α (TNF-α).
포장
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
기타 정보
Sales restrictions may apply.
관련 제품
제품 번호
설명
가격
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Lact.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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시험 성적서(COA)
Lot/Batch Number
Sorry, we don't have COAs for this product available online at this time.
If you need assistance, please contact 고객 지원 부서
Umair Sohail et al.
Clinics in liver disease, 16(4), 717-736 (2012-10-30)
Alcoholic hepatitis is a form of severe, cholestatic liver disease that results from consumption of large amount of alcohol during a sustained period of time in a subset of alcoholics. Symptoms could be mild and nonspecific to more severe. The diagnosis
Cheng-Chung Fang et al.
PloS one, 7(9), e44765-e44765 (2012-10-03)
Excessive fibrin deposition in the peritoneum is thought to be involved in the development of encapsulating peritoneal sclerosis (EPS), an important cause of morbidity and mortality in peritoneal dialysis patients. We investigated fibrin-induced epithelial-to-mesenchymal transition (EMT) of peritoneal mesothelial cells
Alejandro Bravo-Cuellar et al.
Journal of biomedical science, 20, 13-13 (2013-03-01)
In Oncology, the resistance of the cancerous cells to chemotherapy continues to be the principal limitation. The nuclear factor-kappa B (NF-κB) transcription factor plays an important role in tumor escape and resistance to chemotherapy and this factor regulates several pathways
Saad Hamama et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 105(3), 305-312 (2012-10-02)
Radiation-induced fibrosis is a serious late complication of radiotherapy. Pentoxifylline-vitamin E has proven effective and safe in clinical trials in the treatment of fibrosis, while the molecular mechanism of its activity is yet unexplored. Ten patients suffering from radiation-induced enteropathy
John M Akudugu et al.
International journal of radiation biology, 89(6), 462-470 (2013-02-01)
The mode by which the xanthine derivative, pentoxifylline, induces a radiosensitizing effect in cell cultures is a key and controversial radiobiological issue and requires further elucidation. Six human glioblastoma cell lines were tested for the effect of pentoxifylline treatment at
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