추천 제품
Grade
analytical standard
Quality Level
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
forensics and toxicology
pharmaceutical (small molecule)
형식
neat
SMILES string
Cl.Cl.Cc1cc(nnc1NCCN2CCOCC2)-c3ccccc3
InChI
1S/C17H22N4O.2ClH/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21;;/h2-6,13H,7-12H2,1H3,(H,18,20);2*1H
InChI key
GNUCGROXDZMCJI-UHFFFAOYSA-N
유전자 정보
human ... ACHE(43) , CHRM1(1128) , DRD2(1813) , HTR2B(3357) , HTR2C(3358) , MAOA(4128) , SLC6A4(6532)
rat ... Ache(83817) , Camk2a(25400) , Prkca(24680)
애플리케이션
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
생화학적/생리학적 작용
Antidepressant
가장 최신 버전 중 하나를 선택하세요:
J G Edwards et al.
British journal of clinical pharmacology, 42(4), 491-498 (1996-10-01)
1. A double-blind, multicentre study comparing the efficacy and safety of minaprine and amitriptyline in patients with major depression was carried out. Five hundred and thirty-one patients were randomly assigned to treatment with either minaprine 100 mg, 200 mg or
S Cabib et al.
Psychopharmacology, 121(1), 73-80 (1995-09-01)
Different types of clinically effective antidepressants prevent the behavioral effects of experimental stress, and some of these treatments affect mesolimbic dopamine (DA) functioning. Animal studies have demonstrated that repeated psychostimulant administration and repeated or chronic stressful experiences also affect mesolimbic
Y Karasawa et al.
Physiology & behavior, 52(1), 141-147 (1992-07-01)
We attempted to determine if the cholinomimetic activity of the psychotropic drug minaprine was related to the amelioration of the delayed neuronal death induced by cerebral ischemia in Mongolian gerbils. Minaprine improved the passive avoidance deficit induced by cerebral ischemia
T R Norman et al.
The Australian and New Zealand journal of psychiatry, 26(1), 73-81 (1992-03-01)
A review of the clinical efficacy of four structurally distinct antidepressant drugs is presented. Their antidepressant activity can be rationalised within current pharmacological hypotheses of drug action, despite markedly different effects on "in vitro" testing. Fluoxetine, a specific serotonin re-uptake
C A Lorenzini et al.
Pharmacology, biochemistry, and behavior, 45(2), 481-485 (1993-06-01)
The nootropic activity of 3-(2-morpholino-ethylamino)-4-methyl-6-phenyl-pyridazine dihydrochloride (minaprine) has been investigated in intact male, adult Long Evans rats by means of an active avoidance paradigm. In the light-dark box apparatus, the rat had to learn the active avoidance response of going
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