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Merck
모든 사진(1)

문서

M0513

Supelco

Megestrol acetate

analytical standard, for drug analysis

동의어(들):

17α-Acetoxy-6-methyl-4,6-pregnadiene-3,20-dione, 17α-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-acetate, 17α-Hydroxy-6-methyl-6-dehydroprogesterone 17-acetate, Megestrol 17-acetate

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About This Item

실험식(Hill 표기법):
C24H32O4
CAS Number:
Molecular Weight:
384.51
Beilstein:
1917291
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard, for drug analysis

Quality Level

분석

≥99% (HPLC)

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
veterinary

형식

neat

SMILES string

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C

InChI

1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1

InChI key

RQZAXGRLVPAYTJ-GQFGMJRRSA-N

유전자 정보

human ... PGR(5241)

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일반 설명

Megestrol acetate is a commonly used synthetically prepared glucosteroid, which possesses anti-inflammatory property.

애플리케이션

Megestrol acetate may be used as a reference standard for the determination of megestrol acetate in human serum using reversed-phase high performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


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문서 라이브러리 방문

Handbook of Clinical Nutrition and Aging (2009)
Determination of megestrol acetate and cyproterone acetate in serum of patients with advanced breast cancer by high-performance liquid chromatography
Dikkeschei.D.L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 529, 145-154 (1990)
Yo Han Kim et al.
Clinical therapeutics, 37(2), 439-447 (2014-12-03)
Megestrol acetate oral suspension is an appetite stimulant indicated for cachexia. It is available in a conventional formulation and as a nanocrystal dispersion. The aim of this study was to compare the tolerability and pharmacokinetics of these formulations under fed
Navdha Mittal et al.
PloS one, 9(10), e110410-e110410 (2014-10-24)
Resistance to progestin treatment is a major hurdle in the treatment of advanced and reoccurring endometrial cancer. Fenretinide is a synthetic retinoid that has been evaluated in clinical trials as a cancer therapeutic and chemo-preventive agent. Fenretinide has been established
Francisco J Prado-Prado et al.
Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27)
There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one parasite species. Consequently, predicting the probability with which a drug is active against

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