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Merck
모든 사진(1)

주요 문서

B1141000

Bleomycin sulfate

European Pharmacopoeia (EP) Reference Standard

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크기 선택

7 MG
₩267,554

₩267,554

출고 가능일2025년 4월 15일세부사항

벌크 견적 요청
모든 사진(1)

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7 MG
₩267,554

About This Item

CAS Number:
9041-93-4
MDL number:
MFCD00070310
UNSPSC 코드:
41116107
NACRES:
NA.24

₩267,554

출고 가능일2025년 4월 15일세부사항

벌크 견적 요청

Grade

pharmaceutical primary standard

API family

bleomycin

제조업체/상표

EDQM

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

−20°C

SMILES string

[S+](CCCNC(=O)c1nc([s]c1)c2nc([s]c2)CCNC(=O)C(NC(=O)C(C(O)C(NC(=O)C(NC(=O)c6nc(nc(c6C)N)C(NCC(N)C(=O)N)CC(=O)N)C(O[C@@H]4O[C@H]([C@H]([C@@H]([C@@H]4O[C@H]5O[C@@H]([C@H]([C@@H]([C@@H]5O)O\C(=N\[H])\[O-])O)CO)O)O)CO)c3[nH]cnc3)C)C)C(O)C)(C)C.[S](=O)(=O)(O)O

InChI

1S/C55H83N17O21S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/t21?,22?,23?,24?,25?,29-,30+,34?,35?,36?,37+,38+,39-,40-,41?,42-,43-,53+,54-;/m0./s1

InChI key

WUIABRMSWOKTOF-OCBSMOPSSA-N

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관련 카테고리

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Bleomycin sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

면책조항

Sales restrictions may apply.

픽토그램

Health hazard
GHS08

신호어

Danger

유해 및 위험 성명서

H340,H351,H361fd

Hazard Classifications

Carc. 2 - Muta. 1B - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

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문서 라이브러리 방문

Sebastian Willenborg et al.
The Journal of investigative dermatology, 134(7), 2005-2015 (2014-01-11)
Conclusive evidence for the impact of mast cells (MCs) in skin repair is still lacking. Studies in mice examining the role of MC function in the physiology and pathology of skin regenerative processes have obtained contradictory results. To clarify the
Ying Meng et al.
American journal of respiratory cell and molecular biology, 50(4), 723-736 (2013-10-31)
Accumulating evidence has demonstrated that up-regulation of the angiotensin (Ang)-converting enzyme (ACE)/AngII/AngII type 1 receptor (AT1R) axis aggravates pulmonary fibrosis. The recently discovered ACE2/Ang-(1-7)/Mas axis, which counteracts the activity of the ACE/AngII/AT1R axis, has been shown to protect against pulmonary
Andrea C Lo et al.
International journal of radiation oncology, biology, physics, 88(5), 1011-1018 (2014-03-26)
We report long-term outcomes and complications of craniopharyngioma patients referred to our institution. Between 1971 and 2010, 123 consecutive patients received primary treatment for craniopharyngioma in British Columbia and were referred to our institution. The median age was 30 years
Jie-jie Geng et al.
Biochimica et biophysica acta, 1842(9), 1770-1782 (2014-06-17)
Lung interstitial fibrosis is a chronic lung disease, and few effective therapies are available to halt or reverse the progression of the disease. In murine and human lung fibrosis, the expression of CD147 is increased. However, the role of CD147
Vincent Murray et al.
Cellular and molecular life sciences : CMLS, 71(8), 1505-1512 (2013-08-29)
The genome-wide pattern of DNA cleavage at transcription start sites (TSSs) for the anti-tumor drug bleomycin was examined in human HeLa cells using next-generation DNA sequencing. It was found that actively transcribed genes were preferentially cleaved compared with non-transcribed genes.
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질문

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 답변

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 답변

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. We bought Bleomycin sulfate (B1141000). Can we convert it from mg to unit?

    1 답변

    1. This is a product of the European Pharmacopoeia. The activity is reported in the supplier Leaflet. The current shipping lot has an activity of 14,015 IU per 7 mg vial. Please see the link below to review the supplier product page:
      https://crs.edqm.eu/db/4DCGI/View=B1141000

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  4. bonjour, quelle quantité de bléomycine il y a t'il dans un lot ?

    1 답변

    1. This is a product of the European Pharmacopoeia. Batch sizes for this material are not reported. The product is offered in a 7mg package size.

      Please see the link below for more information:
      https://crs.edqm.eu/db/4DCGI/search?vSelectName=2&vContains=1&vtUserName=B1141000&OK=Search&vTypeCRS=

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