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Merck
모든 사진(3)

문서

A3035

Sigma-Aldrich

Acetaminophen

analytical standard

동의어(들):

4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

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모든 사진(3)

About This Item

Linear Formula:
CH3CONHC6H4OH
CAS Number:
103-90-2
Molecular Weight:
151.16
Beilstein:
2208089
EC Number:
203-157-5
MDL number:
MFCD00002328
UNSPSC 코드:
41116107
PubChem Substance ID:
24890717
NACRES:
NA.21

Grade

analytical standard

Quality Level

300

형태

powder

포장

vial of 1 g

기술

HPLC: suitable
gas chromatography (GC): suitable

mp

168-172 °C (lit.)

응용 분야

forensics and toxicology
pharmaceutical (small molecule)
veterinary

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

유전자 정보

human ... FAAH(2166) , PTGS1(5742) , PTGS2(5743) , TRPV1(7442)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Analgesic.

포장

Supplied in amber screw-cap vials

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H302

예방조치 성명서

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

364.3 °F - Pensky-Martens closed cup

Flash Point (°C)

184.6 °C - Pensky-Martens closed cup

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

시험 성적서(COA)

Lot/Batch Number
0000373099
0000373100
0000366464
0000321410
0000373100

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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문서 라이브러리 방문

Karel Allegaert et al.
Archives of disease in childhood, 98(6), 462-466 (2013-04-23)
There remains a need for alternative medical treatments for patent ductus arteriosus (PDA) closure in extreme preterm neonates because of therapeutic failure and adverse effects associated with non-selective cyclo-oxygenase inhibitors. Reports of an association between paracetamol exposure and PDA closure
Garry G Graham et al.
Drug safety, 28(3), 227-240 (2005-03-01)
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
Garry G Graham et al.
Inflammopharmacology, 21(3), 201-232 (2013-05-31)
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors. Paracetamol is, on average, a weaker analgesic than NSAIDs or COX-2 selective
Edward Munsterhjelm et al.
Anesthesiology, 103(4), 712-717 (2005-09-30)
Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system, and acetaminophen is traditionally not considered to influence platelet function. The authors studied the dose-dependent inhibition of platelet
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