A0325450

Alfacalcidol

European Pharmacopoeia (EP) Reference Standard

• 동의어(들): 1α-Hydroxyvitamin D₃, 1α-Hydroxycholecalciferol, Alfacalcidol
• 실험식(Hill 표기법): C₂₇H₄₄O₂
• CAS Number: 41294-56-8
• Molecular Weight: 400.64
• MDL number: MFCD00868328
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329770599
• NACRES: NA.24

속성

• 생물학적 소스: synthetic
• Grade: pharmaceutical primary standard
• Agency: EP
• API family: alfacalcidol
• 양식: solid
• 제조업체/상표: EDQM
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• 저장 온도: −20°C
• SMILES string: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C
• InChI: 1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
• InChI key: OFHCOWSQAMBJIW-AVJTYSNKSA-N
• 유전자 정보: human ... VDR(7421)

설명

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the authority of the issuing pharmacopoeia. For further information and support please go to the website of the issuing pharmacopoeia.

Alfacalcidol is an active metabolite of vitamin D, used as a vitamin supplement due to it longer half-life. It is found to be effective in regulating calcium balance/bone metabolism.[1]

애플리케이션

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

생화학적/생리학적 작용

Synthetic vitamin D₃ analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

기타 정보

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 1 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable