추천 제품
Quality Level
Grade
analytical standard
분석
≥98.5% (HPLC)
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
불순물
≤8.0% water
mp
~260 °C
응용 분야
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
형식
neat
저장 온도
2-8°C
SMILES string
Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
InChI
1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
InChI key
VGEREEWJJVICBM-UHFFFAOYSA-N
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일반 설명
Phloretin is a dihydrochalcone flavonoid with antioxidant activity usually found in apples and apple-derived products. It is extensively used for peroxynitrite scavenging and the inhibition of lipid peroxidation.
Major polyphenol found in apple; aglycone of phloridzin.
애플리케이션
Phloretin may be used as an internal standard for the determination of sterols and diterpenoids in brown algae using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
생화학적/생리학적 작용
Reacts with vic-dicarbonyl compounds such as glyoxal and methylglyoxal, preventing cytotoxic conjugation with biological macromolecules.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Determination of sterols and diterpenoids from brown algae (Cystoseiraceae).
Journal of Chromatography A, 588(1-2), 99-105 (1991)
Bioavailability of phloretin and phloridzin in rats.
The Journal of Nutrition, 131(12), 3227-3230 (2001)
American journal of physiology. Regulatory, integrative and comparative physiology, 307(3), R237-R247 (2014-06-13)
Glucose is a major substrate for milk synthesis and is taken up from the blood by mammary epithelial cells (MECs) through facilitative glucose transporters (GLUTs). The expression levels of GLUT1 and GLUT8 are upregulated dramatically in the mammary gland from
Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(10), 1208-1215 (2014-06-17)
Bone-remodeling imbalance induced by increased osteoclast formation and bone resorption is known to cause skeletal diseases such as osteoporosis. The reduction of estrogen levels at menopause is one of the strongest risk factors developing postmenopausal osteoporosis. This study investigated osteoprotective
Biochemical and biophysical research communications, 295(1), 9-13 (2002-06-27)
Phloretin is a dihydrochalcone flavonoid that displays a potent antioxidant activity in peroxynitrite scavenging and the inhibition of lipid peroxidation. Comparison with structurally related compounds revealed that the antioxidant pharmacophore of phloretin is 2,6-dihydroxyacetophenone. The potent activity of 2,6-dihydroxyacetophenone is
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