90833

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid

analytical standard

• 동의어(들): 3-Carboxy-4-methyl-5-propyl-2-furanpropionic acid, CMPF, Propylurofuranic acid
• 실험식(Hill 표기법): C₁₂H₁₆O₅
• CAS Number: 86879-39-2
• Molecular Weight: 240.25
• MDL number: MFCD08436079
• UNSPSC 코드: 12352106
• NACRES: NB.21

속성

• Grade: analytical standard
• Quality Level: 100
• 분석: ≥95.0% (HPLC)
• 유통기한: limited shelf life, expiry date on the label
• 응용 분야: clinical testing
• 형식: neat
• 저장 온도: 2-8°C
• SMILES string: OC(CCC1=C(C(O)=O)C(C)=C(CCC)O1)=O
• InChI: 1S/C12H16O5/c1-3-4-8-7(2)11(12(15)16)9(17-8)5-6-10(13)14/h3-6H2,1-2H3,(H,13,14)(H,15,16)
• InChI key: WMCQWXZMVIETAO-UHFFFAOYSA-N

설명

일반 설명

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), a major metabolite of furan fatty acids,[1][2] is a uremic toxin (UT), excreted into the urine via organic,anion transporters under physiological conditions.[2] It is mostly reported to be accumulated in chronic kidney disease (CKD) patients.[3] Monitoring of CMPF may be important to predict organic anion transporting polypeptide (OATP)1B activity in CKD patients as studies have implicated a decreased trend in (OATP)1B activity in patients with this uremic toxin.[3] It is also found to be in increased concentrations, for patients who progress from prediabetes to type 2 diabetes, patients with renal failure, polyunsaturated fatty acids with high-temperature cooking and subjects who consume fish or fish oil.[1][2]

애플리케이션

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid may be used as an analytical reference standard for the quantification of the analyte in human plasma samples using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS).[3]

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3