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Merck
모든 사진(1)

주요 문서

70127

Sigma-Aldrich

Naloxone hydrochloride dihydrate

≥99.0% (TLC)

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About This Item

실험식(Hill 표기법):
C19H21NO4 · HCl · 2H2O
CAS Number:
Molecular Weight:
399.87
Beilstein:
6260807
EC Number:
MDL number:
UNSPSC 코드:
12352202

분석

≥99.0% (TLC)

저장 온도

2-8°C

SMILES string

O.O.Cl.Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC=C

InChI

1S/C19H21NO4.ClH.2H2O/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;;;/h2-4,14,17,21,23H,1,5-10H2;1H;2*1H2/t14-,17+,18+,19-;;;/m1.../s1

InChI key

TXMZWEASFRBVKY-IOQDSZRYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Displaces morphine and other opiate agonists from the opiate receptor. In studies on the opiate receptor

기타 정보

Potent opiate antagonist.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

C Mollereau et al.
The Journal of biological chemistry, 263(34), 18003-18008 (1988-12-05)
When assayed for specific opiate binding in the presence of 120 mM NaCl, digitonin extracts from frog (Rana ridibunda) brain membranes were found to contain about the same quantity (0.5 pmol/mg of protein) of high (Kdh = 0.4 nM) and
T Costa et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(19), 7321-7325 (1989-10-01)
According to classical models of drug-receptor interactions, competitive antagonists share with agonists the ability to bind to a common site on the receptor molecule. However, they are different from agonists, as they cannot trigger the "stimulus" that leads to biological
Yumei Liu et al.
PloS one, 8(1), e51573-e51573 (2013-02-06)
Previously, we demonstrated that electroacupuncture (EA) decreased lymphocyte infiltration into the spinal cords of rats presenting with experimental autoimmune encephalomyelitis (EAE), a disease model used in the study of multiple sclerosis (MS). The aim of this study was to characterize
Thirimon Moe-Byrne et al.
The Cochrane database of systematic reviews, 2(2), CD003483-CD003483 (2013-03-02)
Naloxone, a specific opiate antagonist, is available for the treatment of newborn infants with cardiorespiratory or neurological depression that may be due to intrauterine exposure to opiate. It is unclear whether newborn infants may benefit from this therapy and whether
Delia Aguado et al.
Anesthesiology, 118(5), 1160-1169 (2013-02-15)
Opioid antagonists at ultra-low doses have been used with opioid agonists to prevent or limit opioid tolerance. The aim of this study was to evaluate whether an ultra-low dose of naloxone combined with remifentanil could block opioid-induced hyperalgesia and tolerance

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