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Merck
모든 사진(1)

문서

38490

Supelco

5,5-Dimethyl-1,3-cyclohexanedione

for HPLC derivatization, for the determination of aldehyde formaldehyde, ≥99.0%

동의어(들):

Dimedone, Methone

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About This Item

Linear Formula:
(CH3)2C6H6(=O)2
CAS Number:
Molecular Weight:
140.18
Beilstein:
471489
EC Number:
MDL number:
UNSPSC 코드:
12164500
PubChem Substance ID:
NACRES:
NA.21

Grade

for HPLC derivatization

Quality Level

분석

≥99.0% (GC)
≥99.0%

품질

for the determination of aldehyde formaldehyde

mp

146-148 °C (lit.)

응용 분야

general analytical

SMILES string

CC1(C)CC(=O)CC(=O)C1

InChI

1S/C8H12O2/c1-8(2)4-6(9)3-7(10)5-8/h3-5H2,1-2H3

InChI key

BADXJIPKFRBFOT-UHFFFAOYSA-N

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일반 설명

5,5-dimethyl-1,3-cyclohexanedione (Dimedone) is basically a highly sensitive and very specific reagent used for the determination of aldehydes. It is highly advantageous as it is environment friendly, give high yields and is a simple workup procedure.

애플리케이션

5,5-dimethyl-1,3-cyclohexanedione may be used in condensation reaction with aromatic aldehyde in ethylene glycol. It may be also be used in trace analysis of aldehydes by HPLC.

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Solid-State Condensation Reactions Between Aldehydes and 5, 5-Dimethyl-1, 3-cyclohexanedione by Grinding at Room Temperature.
Tong-shou J
Synthetic Communications, 35 (17), 2339-2345 (2005)
Jesse C Patterson et al.
Cell systems, 8(2), 163-167 (2019-02-25)
Although elevated levels of reactive oxygen species (ROS) have been observed in cancer cells and cancer cells aberrantly proliferate, it is not known whether the level of reactive oxygen species and the accumulation of oxidative damage to macromolecules vary across
Trace analysis of aldehydes by reversed-phase high-performance liquid chromatography and precolumn fluorigenic labeling with 5, 5-dimethyl-1, 3-cyclohexanedione.
Kenneth M
Journal of Chromatography A, 256, 243-252 (1983)
Kimberly J Nelson et al.
Methods in enzymology, 473, 95-115 (2010-06-02)
Reversible thiol modification is a major component of the modulation of cell-signaling pathways by reactive oxygen species. Hydrogen peroxide, peroxynitrite, or lipid hydroperoxides are all able to oxidize cysteines to form cysteine sulfenic acids; this reactive intermediate can be directly
Katie E Crump et al.
European journal of immunology, 42(8), 2152-2164 (2012-06-08)
B-cell receptor (BCR) ligation generates reactive oxygen intermediates (ROIs) that play a role in cellular responses. Although ROIs can oxidize all macromolecules, it was unclear which modifications control B-cell responses. In this study, we demonstrate the importance of the first

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