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Merck
모든 사진(2)

문서

18571

Supelco

Amentoflavone

analytical standard

동의어(들):

Didemethyl-ginkgetin, I3′,II8-Biapigenin, Tridemethylsciadopitysin

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About This Item

실험식(Hill 표기법):
C30H18O10
CAS Number:
Molecular Weight:
538.46
Beilstein:
380244
MDL number:
UNSPSC 코드:
85151701
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

분석

≥98.0% (HPLC)

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

food and beverages

형식

neat

저장 온도

2-8°C

SMILES string

Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)c(c3O2)-c4cc(ccc4O)C5=CC(=O)c6c(O)cc(O)cc6O5

InChI

1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H

InChI key

YUSWMAULDXZHPY-UHFFFAOYSA-N

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관련 카테고리

일반 설명

Amentoflavone is a flavonoid which is used as an antiviral agent.

애플리케이션

It was used as a standard during HPLC analysis done for separating chemical components.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

기타 정보

This compound is commonly found in plants of the genus: ginkgo hypericum

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

S C Ma et al.
Biological & pharmaceutical bulletin, 24(3), 311-312 (2001-03-21)
Amentoflavone and three other flavonoids were isolated from the ethanol extract of Selaginella sinensis. Amentoflavone showed potent antiviral activity against respiratory syncytial virus (RSV), with an IC50 of 5.5 microg/ml. The contents of amentoflavone in nine species of Selaginella were
Yuchi Zhang et al.
Journal of separation science, 33(17-18), 2743-2748 (2010-08-24)
A novel gradient elution was efficiently utilized for the separation of the chemical components with a wide range of polarity from the mixed extract of the Chinese medicinal herb Apocynum venetum or mixed standards by high-speed counter-current chromatography. Three sets
Jen-Sheng Pei et al.
In vivo (Athens, Greece), 26(6), 963-970 (2012-11-20)
Amentoflavone, isolated from an ethyl acetate extract of the whole plant of Selaginella tamariscina, a traditional herb, may exhibit antitumor activity. The aim of this study was to investigate the anticancer mechanism(s) of amentoflavone, such as mitochondria-mediated apoptotic cell death
Steffi Wilsky et al.
Archives of virology, 157(2), 259-269 (2011-11-15)
Coxsackievirus B3 (CVB3) is a human pathogen that causes acute and chronic infections, but an antiviral drug to treat these diseases has not yet been developed for clinical use. Several intracellular pathways are altered to assist viral transcription, RNA replication
Shih-Chang Tsai et al.
Oncology reports, 28(3), 1096-1102 (2012-06-28)
Calophyllum inophyllum L. has been used as folk medicine in the treatment of ocular burn and it has demonstrated potential to be an anti-inflammatory agent. The aim of this study was to explore the anti-inflammatory activities of an acetone extract

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