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Merck
모든 사진(1)

문서

00170580

Ginsenoside Rb1

primary reference standard

동의어(들):

2-O-β-Glucopyranosyl-(3β,12β)-20-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl β-D-glucopyranoside, Arasaponin E1, Gynosaponin C, Gypenoside III, Notoginsenoside Rb1, Panaxoside Rb1, Sanchinoside E1, Sanchinoside Rb1

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About This Item

실험식(Hill 표기법):
C54H92O23
CAS Number:
Molecular Weight:
1109.29
EC Number:
MDL number:
UNSPSC 코드:
85151701
PubChem Substance ID:
NACRES:
NA.24

Grade

primary reference standard

유통기한

limited shelf life, expiry date on the label

제조업체/상표

HWI

기술

HPLC: suitable
gas chromatography (GC): suitable

SMILES string

C\C(C)=C\CC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)[C@@H]3[C@H](O)C[C@@H]5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)[C@@H]6CC[C@@]45C

InChI

1S/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53+,54-/m0/s1

InChI key

GZYPWOGIYAIIPV-JBDTYSNRSA-N

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일반 설명

Produced and qualified by HWI pharma services GmbH.
Exact content measured by quantitative NMR can be found on the certificate.

Ginsenoside Rb1 is one of the primary constituents of traditional Chinese medicine, Ginseng. It belongs to the group of triterpene saponins called ginsenosides and pharmacologically, it is one of the most active dammarane-type ginsenosides. It is known to have anti-tumor, anti-oxidant, anti-inflammatory, and cytoprotective properties.

애플리케이션

The primary reference standard can be used for identification, assay, and purity testing, method development, and validation.It can also be used as follows:
  • Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of ginsenoside Rb1, naringin, ginsenoside Rb2, and oridonin in rat plasma samples after administrating them weifuchun tablets
  • Multi-residue analysis of baicalin, baicalein, wogonoside, wogonin, scutellarin, berberine, coptisine, ginsenoside Rb1, and ginsenoside Re in biological samples of rat plasma by liquid chromatographic-tandem mass spectrometric (LC/MS/MS) method
  • Analysis of traditional Chinese herbal decoctions of Dushen Tang and Shenfu Tang for the quantification of 12 ginsenosides by UPLC-MS/MS technique
  • Analysis of rhizomes and roots of ginseng for the detection of 131 ginsenosides by UHPLC combined with a diode-array detector and quadrupole/time of flight tandem mass spectrometry (DAD-QTOF-MS/MS), along with the further determination of 19 ginsenosides by HPLC coupled with electrospray ionization-mass spectrometric detection

기타 정보

This compound is commonly found in plants of the genus: panax

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서

Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.

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