10602370001

Plasmin, bovine

from bovine plasma

• 동의어(들): Plasmin
• 효소 위원회 번호: 3.4.21.7 (BRENDA, IUBMB)
• UNSPSC 코드: 12352204

속성

• 생물학적 소스: bovine plasma
• 양식: suspension
• 특이 활성도: ≥2 units/mg protein (At 25 °C with Chromozym PL as the substrate.)
• 분자량: M_r ~85 kDa
• 포장: pkg of 1 mL (5 U)
• 제조업체/상표: Roche
• 최적 pH: 8.9
• 배송 상태: wet ice
• 저장 온도: 2-8°C

설명

일반 설명

Plasmin is derived from the proteolytic cleavage of its precursor plasminogen. Human Plasmin is made up of two polypeptide chains. The polypeptide chains are connected via disulfide bridges.

특이성

Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.

애플리케이션

Plasmin from bovine has been used as a standard for assessing plasmin biosensors and for proteolytic assays.

생화학적/생리학적 작용

Plasmin plays an important role in proteolysis and fibrinolysis. It possesses inflammatory activity. Plasmin is also involved in the hydrolysis of peptide bonds following arginine or lysine. It also cleaves hormones like glucagon, thrombopoietin and growth hormones. Plasmin plays a role in cleavage of complement factors like C3 and C5, coagulation factors V and VIII, matrix proteins, growth factors, E-cadherins and metalloproteinase.

물리적 형태

Suspension in 3.2 M ammonium sulfate solution

기타 정보

For life science research only. Not for use in diagnostic procedures.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash