MATRESIQUIM0D

Resiquimod Non-Endotoxin Pyrogen (NEP) Control

for use with PyroMAT^®

• 동의어(들): Imidazoquinolinon
• UNSPSC 코드: 41116129
• NACRES: NA.74

속성

• Agency: EP; JP 4.06; USP
• Quality Level: 400
• 형태: lyophilized
• 응용 분야: pharmaceutical; pyrogen testing
• 호환성: for use with PyroMAT^®
• 배송 상태: ambient
• 저장 온도: −20°C
• 적합성: pyrogenic bacteria

설명

일반 설명

Resiquimod is a non-endotoxin pyrogen which will serve as a positive control during pyrogen testing with PyroMAT^® system.Non- Endotoxin Pyrogen (NEP) Control Resiquimod is an imidazoquinolinone compound possessing a potent anti-viral activity, supplied in a lyophilized form. It is designed to mimic the NEPs of viral origin. Resiquimod Non- Endotoxin Pyrogen (NEP) Control activates TLR7/TLR8 receptor of monocytes and is used as a positive control for PyroMAT^® system. The response to pyrogenic substances is determined by measuring the Interleukin-6 (IL-6) produced by the monocytes using ELISA microplate.

애플리케이션

Resiquimod Non- Endotoxin Pyrogen (NEP) Control can be used as a positive control with the PyroMAT^® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

법적 정보

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable