추천 제품
일반 설명
Aggregating chondroitin sulfate proteoglycan or aggrecan, is one of the most studied proteoglycans. Many individual monomers of aggrecan bind to hyaluronic acid to form an aggregate, the monomer is known as aggrecan. The aggregates are comprised of up to 100 monomers attached to a single chain of hyaluronic acid. The high content of negatively charged polysaccharide chains contributes to the osmotic swelling of cartilage and in combination with intact collagen fibers results in articular cartilage resistance to compressive forces and high tensile strength. Aggrecan is abundant in articular cartilage and compromises 10% of its dry weight.
면역원
Reduced and alkylated Aggrecan isolated from Swarm Rat Chondrosarcoma
애플리케이션
This Anti-Aggrecan Antibody, clone 1-C-6 is validated for use in IH, WB for the detection of Aggrecan.
Western Blot Analysis: 1 µg/mL from a representative lot detected Aggrecan on 10 µg of A1D4 protein fraction from Bovine tissue.
품질
Evaluated by Immunohistochemistry in normal mouse cartilage and normal rat cartilage tissues.
Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Aggrecan in normal mouse cartilage and normal rat cartilage tissues.
Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Aggrecan in normal mouse cartilage and normal rat cartilage tissues.
표적 설명
Various
물리적 형태
Format: Purified
분석 메모
Control
Normal mouse cartilage and normal rat cartilage tissues
Normal mouse cartilage and normal rat cartilage tissues
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Takamitsu Maruyama et al.
Science advances, 8(48), eadd6172-eadd6172 (2022-12-01)
Skeletal precursors are mesenchymal in origin and can give rise to distinct sublineages. Their lineage commitment is modulated by various signaling pathways. The importance of Wnt signaling in skeletal lineage commitment has been implicated by the study of β-catenin-deficient mouse
Thomas H Ambrosi et al.
Cell stem cell, 20(6), 771-784 (2017-03-24)
Aging and obesity induce ectopic adipocyte accumulation in bone marrow cavities. This process is thought to impair osteogenic and hematopoietic regeneration. Here we specify the cellular identities of the adipogenic and osteogenic lineages of the bone. While aging impairs the
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